Triclocarban (TCC), which is used as an antimicrobial agent in personal care products, has been widely detected in aquatic ecosystems. However, the consequence of TCC exposure on embryo development is still elusive. Here, by using zebrafish embryos, we aimed to understand the developmental defects caused by TCC exposure. After exposure to 0.3, 30, and 300 μg/L TCC from 4-hour postfertilization (hpf) to 120 hpf, we observed that TCC exposure significantly increased the mortality and malformation, delayed hatching, and reduced body length. Exposure to TCC also affected the heart rate and expressions of cardiac development-related genes in zebrafish embryos. In addition, TCC exposure altered the expressions of the genes involved in hormonal pathways, indicating its endocrine disrupting effects. In sum, our data highlight the impact of TCC on embryo development and its interference with the hormone system of zebrafish.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jbt.22289 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Transitional Cell Carcinoma Arising From the Renal Allograft: A Case Series and Review of the Literature.
Cureus
November 2024
Department of Surgery, Rush University Medical Center, Chicago, USA.
Transitional cell carcinoma (TCC) of the urinary tract appears more commonly among the transplant population. The increased incidence of TCC has been primarily associated with the male gender, BK virus (BKV), and smoking. We report a case series and comprehensive review of the literature.
View Article and Find Full Text PDFExposure to Multiple Endocrine-Disrupting Chemicals and Associations with Female Infertility: A Case-Control Study.
Environ Health (Wash)
December 2024
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Parabens (PBs) and their metabolites (MBs), triclocarban (TCC), triclosan (TCS), bisphenols (BPs), benzophenones (BzPs), and phthalate metabolites (mPAEs) are typical endocrine-disrupting chemicals (EDCs) used in industrial production and daily life. Studies have suggested that these EDCs affect the reproductive system and may cause infertility; however, epidemiological evidence linking EDC exposure to infertility is still lacking. Herein, a total of 302 serum samples from women of reproductive age were collected, and six categories of typical EDCs were analyzed.
View Article and Find Full Text PDFBehavioural, Teratogenic and Genotoxic Effects of Antibacterial Compounds, Triclocarban and Triclosan, in Hydra vulgaris.
J Appl Toxicol
November 2024
Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, India.
Triclocarban (TCC) and triclosan (TCS) are antibacterial compounds used in household, veterinary, industrial and personal care products, which are known to be environmental pollutants and also toxic to organisms. The toxicological effects of these antibacterial chemicals on higher organisms have been studied in detail. But in lower invertebrates like hydra, it is still rare and yet to be explored.
View Article and Find Full Text PDFTele-Critical Care, Severity of Illness, and 30-Day Mortality Risk: A Retrospective, Cohort Analysis.
Telemed J E Health
November 2024
Division of Intensive Care and Resuscitation, Department of Anesthesiology, Integrated Hospital Care Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Studies have shown that tele-critical care (TCC) improves outcomes in intensive care unit (ICU) settings with low baseline performance. Evidence also suggests that TCC outcomes may be modified by heterogenous baseline severity of illness. We examined the association of admission Acute Physiology and Chronic Health Evaluation IV (APACHE IV) score quartiles (APQ1-APQ4) and TCC exposure with 30-day mortality.
View Article and Find Full Text PDFMulti-Stimuli Responsive Viologen-Imprinted Polyvinyl Alcohol and Tricarboxy Cellulose Nanocomposite Hydrogels.
Sensors (Basel)
October 2024
Department of Chemistry, College of Science, Qassim University, Buraidah 51452, Saudi Arabia.
Photochromic inks have shown disadvantages, such as poor durability and high cost. Self-healable hydrogels have shown photostability and durability. Herein, a viologen-based covalent polymer was printed onto a paper surface toward the development of a multi-stimuli responsive chromogenic sheet with thermochromic, photochromic, and vapochromic properties.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!