A Pd cross-coupling approach for the synthesis of N-aryl-oxetanylamines has been developed. This method provides new building blocks potentially useful in medicinal chemistry as amide bioisosteres. The reactions are conducted in water employing the renewable feedstock surfactant TPGS-750-M.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c8cc09110b | DOI Listing |
Publication Analysis
Top Keywords
water n-arylation
4
n-arylation oxetanylamines
4
oxetanylamines preparation
4
preparation n-aryl-oxetanylamines
4
n-aryl-oxetanylamines aryl-amide
4
aryl-amide isosteres
4
isosteres cross-coupling
4
cross-coupling approach
4
approach synthesis
4
synthesis n-aryl-oxetanylamines
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!