[Anti-N-methyl-D-aspartate receptor encephalitis, an essential differential diagnosis in psychiatry: a case report.].

Neuropsychiatr

1. Psychiatrische Abteilung mit Zentrum für Psychotherapie und Psychosomatik, Sozialmedizinisches Zentrum Baumgartner Höhe, Otto Wagner Spital, Baumgartner Höhe 1, 1140, Wien, Österreich.

Published: June 2019

AI Article Synopsis

  • Anti-N-methyl-D-aspartate receptor encephalitis is a newly recognized condition that presents with significant psychiatric symptoms, often leading to misdiagnosis as a psychotic disorder.
  • An 18-year-old female patient illustrates this, as she was initially treated for a psychotic disorder before further testing revealed her true diagnosis of anti-NMDAR encephalitis.
  • Rising awareness among psychiatrists is crucial, as they need to recognize autoimmune encephalitis as a potential differential diagnosis, especially in young women with first-onset psychiatric symptoms alongside neurological signs.

Article Abstract

Anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDAR encephalitis) is a rare and recently discovered disease. Affected patients are initially often referred to psychiatric departments due to prominent neuropsychiatric symptoms.We present the course of the illness of an 18-year-old female patient, who was primarily and for the first time admitted to the 1. Psychiatric Department of the Otto Wagner Hospital Vienna due to a psychotic disorder. With fluctuating clinical course, further diagnostics were performed and the patient was diagnosed with anti-NMDAR encephalitis.Anti-NMDAR encephalitis should especially be considered in young women, who suffer from a first-onset psychotic disorder in combination with neurological and vegetative symptoms.If suspected lumbar puncture is indicated. An interdisciplinary approach is indispensable for this disease and can be a challenge for psychiatrists in charge.Psychiatrists should consider encephalitis, autoimmune encephalitis in particular, as differential diagnosis in clinical practice and get more familiar with these complex conditions.

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Source
http://dx.doi.org/10.1007/s40211-018-0296-8DOI Listing

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