Granular acute lymphoblastic leukemia (ALL) is a rare variant of the disease that is associated with a lower remission rate to standard induction chemotherapy. Flow immunophenotyping, cytogenetics, and molecular diagnostics should be utilized to confirm the diagnosis of ALL versus acute myeloid leukemia (AML) in order to provide appropriate management.
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http://dx.doi.org/10.1002/ccr3.1866 | DOI Listing |
Int J Mol Sci
January 2025
Department of Functional Biochemistry of the Nervous System, Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow 117485, Russia.
Traumatic brain injury (TBI) is one of the primary causes of mortality and disability, with arterial blood pressure being an important factor in the clinical management of TBI. Spontaneously hypertensive rats (SHRs), widely used as a model of essential hypertension and vascular dementia, demonstrate dysfunction of the hypothalamic-pituitary-adrenal axis, which may contribute to glucocorticoid-mediated hippocampal damage. The aim of this study was to assess acute post-TBI seizures, delayed mortality, and hippocampal pathology in SHRs and normotensive Sprague Dawley rats (SDRs).
View Article and Find Full Text PDFCrit Care
January 2025
Intensive Care Unit, Department of Acute Medicine, University Hospital Basel, Petersgraben 5, 4031, Basel, Switzerland.
Background: Conflicting data exist regarding sex-specific outcomes after cardiac arrest. This study investigates sex disparities in the provision of critical care and outcomes of in-hospital (IHCA) and out-of-hospital cardiac arrest (OHCA) patients.
Methods: Analysis of adult cardiac arrest patients admitted to certified Swiss intensive care units (ICUs) (01/2008-12/2022) using the nationwide prospective ICU registry.
J Small Anim Pract
January 2025
Polo Oncologico Veterinario, AniCura Italy Holding S.r.l., Bologna, Italy.
Primary uterine lymphoma is an extremely rare disease. An 11-year-old spayed female domestic short-haired cat presented with a 3-month history of mucopurulent vaginal discharge, lethargy, acute vomiting and constipation. Physical examination revealed vulvar swelling, purulent discharge and a mass in the mid-caudal abdomen.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Department of Occupational and Environmental Health, University of Iowa, Iowa City.
Importance: Hurricanes are associated with a wide range of adverse health effects in the general population and are increasing in frequency and severity due to global climate change. Due to prior military exposures and distinct sociodemographic characteristics, US veterans may be more vulnerable than the general population to negative health effects of hurricanes.
Objective: To evaluate whether acute care mental health visits among US veterans were associated with exposure to hurricanes.
Clin Nephrol Case Stud
December 2024
Nephrology Center and the Okinaka Memorial Institute for Medical Research.
A 47-year-old woman with a 12-year history of anemia and high C-reactive protein (CRP) levels was admitted to our hospital with worsening fatigue and night sweats. She had high levels of immunoglobulin G (IgG; 4182 mg/dL), IgA (630.6 mg/dL), and CRP (7.
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