Background In 621 consecutive prostate cancer patients, the frequency of urinary tract infections (UTI) and marker loss was evaluated. They prophylactically received a single dose of non-broad-spectrum antibiotics and transrectal implantation of three thin needle fiducial markers, Gold Anchor ™ (GA). Methods The occurrence of UTIs, sepsis, hospitalization due to infection, and marker loss after implantation was assessed from the medical records containing notes from physicians and nurses from the day of implantation to the end of 29 fractions. Results UTIs occurred in two (0.3%) of the 621 patients. Neither sepsis nor hospitalization was noted. Loss/drop-out of three markers was noted among 1,863 markers implanted. Conclusion The use of thin needles for the implantation of fiducials appears to reduce the rate of infection despite the use of a single dose of non-broad-spectrum antibiotics as prophylaxis. The marker construct appears to provide stability in the tissues.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318111 | PMC |
| http://dx.doi.org/10.7759/cureus.3526 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Technical Aspects of a National Service for Paediatric Pelvic Brachytherapy.
Clin Oncol (R Coll Radiol)
December 2024
Department of Oncology, University College London Hospitals NHS Foundation Trust, 250 Euston Road, London, NW1 2PG, UK. Electronic address:
Aims: Brachytherapy is advantageous for localised rhabdomyosarcomas in children compared with external beam radiotherapy, sparing close organs at risk with highly conformal dosimetry. A methodology for planning and delivering fractionated high-dose-rate paediatric pelvic brachytherapy is detailed, and the dosimetric parameters are presented. This provides a practical template for radiotherapy departments with a similar patient cohort to implement this treatment technique.
View Article and Find Full Text PDFTowards U-Net-based intraoperative 2D dose prediction in high dose rate prostate brachytherapy.
Brachytherapy
December 2024
Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Lawson Health Research Institute, London, Ontario, Canada; Department of Oncology, Western University, London, Ontario, Canada; London Regional Cancer Program, London, Ontario, Canada. Electronic address:
Background: Poor needle placement in prostate high-dose-rate brachytherapy (HDR-BT) results in sub-optimal dosimetry and mentally predicting these effects during HDR-BT is difficult, creating a barrier to widespread availability of high-quality prostate HDR-BT.
Purpose: To provide earlier feedback on needle implantation quality, we trained machine learning models to predict 2D dosimetry for prostate HDR-BT on axial TRUS images.
Methods And Materials: Clinical treatment plans from 248 prostate HDR-BT patients were retrospectively collected and randomly split 80/20 for training/testing.
Reconstruction errors in clinical intraoperative TRUS-based prostate HDR-BT detected using electromagnetic tracking.
Brachytherapy
January 2025
Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, Netherlands.
Article Synopsis
- - The study aimed to identify errors in transrectal ultrasound (TRUS)-based reconstructions for high-dose-rate brachytherapy in prostate cancer, using an electromagnetic tracking (EMT) system to enhance accuracy during treatment.
- - Out of 265 evaluated needle reconstructions, 23% had minor errors or worse, with 9% classified as major or severe, primarily due to issues like incorrect needle placement and user errors.
- - The findings indicate that one-quarter of the reconstructions had errors exceeding 2mm, highlighting the potential of EMT to help detect and prevent these mistakes, improving patient care without affecting the clinical process.
Instant plan quality prediction on transrectal ultrasound for high-dose-rate prostate brachytherapy.
Brachytherapy
January 2025
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065.
Purpose: We investigated the feasibility of AI to provide an instant feedback of the potential plan quality based on live needle placement, and before planning is initiated.
Materials And Methods: We utilized YOLOv8 to perform automatic organ segmentation and needle detection on 2D transrectal ultrasound images. The segmentation and detection results for each patient were then fed into a plan quality prediction model based on ResNet101.
Proof-of-concept of real-time electromagnetic guidance for gynecologic interstitial catheters in high dose rate brachytherapy.
Phys Imaging Radiat Oncol
October 2024
Radiation Oncology, CHU de Québec - Université Laval, Québec, Canada.
Background And Purpose: The addition of interstitial needles to intracavitary gynecologic (GYN) high dose rate (HDR) brachytherapy has been shown to improve target coverage and organs-at-risk (OAR) sparing. However, no commercial solution allows real-time guidance of interstitial catheter placement. This phantom study aimed to evaluate the feasibility of an electromagnetic (EM) tracking system guidance workflow for GYN HDR brachytherapy treatment in a magnetic resonance imaging (MRI) and real-time transrectal ultrasound (TRUS) fusion scenario.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!