Fish bone foreign body (FFB) impaction in the upper aerodigestive tract is a common cause for emergency department referral. Its management varies in both diagnosis and treatment paradigms. Fish bone foreign bodies are more commonly found in the oropharynx in cases of patients < 40 years old, and in the esophagus in cases of patients > 40 years old. Symptoms are typically non-indicative for the location of the FFB, with the exception of foreign body sensation at/superior to the cervical esophagus. A lack of findings during the physical examination is routinely followed by imaging, with computed tomography (CT) being the preferred modality. In practice, many patients undergo unnecessary imaging studies, including CT scans. To identify patients with suspected fish bone impaction who do not require CT imaging and can be safely discharged. We have searched the PubMed database for the following medical subject headings (MeSH) terms: , AND , , , , and . Our search in the English language yielded 32 papers. Case reports were included, since they highlighted rare and serious complications. In patients > 40 years old suspected of fish bone impaction, non-contrast CT is recommended and should be urgently performed, even in the presence of ambiguous symptoms. However, in patients < 40 years old presenting within 24 hours from ingestion, imaging has little diagnostic value due to the low probability of esophageal fish bones. For this specific subgroup, in the absence of clinical findings, discharge without imaging studies may be considered safe.
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http://dx.doi.org/10.1055/s-0038-1673631 | DOI Listing |
J Fish Biol
January 2025
Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy.
This study investigates the growth and calcification of the appendicular skeleton in Raja asterias (Delaroche, 1809), a member of the Batoidea, to explore the relationship between histomorphology and the mechanics of batoid locomotion within the water column. Although much prior research has focused on the "tessellated pattern" in these fishes, the variable structure of the appendicular skeleton provides fresh insights into the understudied interplay between skeletal histomorphology and the mechanical functions of Batoidea fins. The shape and initial growth of fin cartilage are influenced by the orientation of chondrocyte mitoses prior to mineral deposition, with subsequent calcification playing a pivotal role in shaping skeletal architecture.
View Article and Find Full Text PDFInt J Biol Sci
January 2025
Department of Biology, University of Padova, Padua, Italy.
Stat3 is a transcription factor with a key role in cell proliferation and migration. Using the zebrafish line we showed that the genetic ablation results in a marked decrease of tail fin regrowth, demonstrating that this transcription factor is fundamental in the regeneration process. Stat3 activity is finely modulated by post-translational modifications that occur in several residues of the protein (i.
View Article and Find Full Text PDFInfect Drug Resist
December 2024
Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.
Introduction: Tuberculosis is prevalent in high-burden countries. However, spinal multi-drug resistant tuberculosis (MDR-TB) in patients with normal immune function is a disease that is prone to misdiagnosis and even delayed diagnosis. Recently, we successfully treated one such patient.
View Article and Find Full Text PDFBMC Biol
December 2024
College of Fisheries, Hubei Hongshan Laboratory/Key Lab of Freshwater Animal Breeding, Ministry of Agriculture and Rural Affairs/Engineering Research Center of Green Development for Conventional Aquatic Biological Industry in the Yangtze River Economic Belt, Ministry of Education, Huazhong Agricultural University, No. 1 Shizishan Street, Hongshan District, Wuhan, 430070, Hubei, China.
Background: Intermuscular bones (IBs) are segmental intramembranous ossifications located within myosepta. They share similarities with tendon ossification, a form of heterotopic ossification (HO). The mechanisms underlying IB formation remain incompletely understood.
View Article and Find Full Text PDFBMJ Open
December 2024
Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Gentofte, Denmark.
Introduction: Previous randomised controlled trials (RCTs) have indicated a protective role of pregnancy supplementation with fish oil and high-dose vitamin D, respectively, on offspring asthma, infections and several other disorders in early childhood. However, current evidence is not considered sufficient for recommending these supplements in pregnancy. In two RCTs, we aim to investigate whether these protective effects can be confirmed in larger trials with the goal of changing clinical practice and improving child health.
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