Dendritic cells mature to resist lamin degradation and herpes virus release.

J Cell Biol

Institut National de la Santé et de la Recherche Médicale, U1016, Institut Cochin, Paris, France

Published: February 2019

Herpes simplex viruses bud into the nuclear membrane of infected cells. Turan et al. (2019. https://doi.org/10.1083/jcb.201801151) demonstrate that mature dendritic cells control the peripheral location of lysosomes, reducing autophagic degradation of lamins and inhibiting viral release.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363439PMC
http://dx.doi.org/10.1083/jcb.201812051DOI Listing

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