AI Article Synopsis
Article Abstract
We consider the estimation of the prevalence of a rare disease, and the log-odds ratio for two specified groups of individuals from group testing data. For a low-prevalence disease, the maximum likelihood estimate of the log-odds ratio is severely biased. However, Firth correction to the score function leads to a considerable improvement of the estimator. Also, for a low-prevalence disease, if the diagnostic test is imperfect, the group testing is found to yield more precise estimate of the log-odds ratio than the individual testing.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/bimj.201800125 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Nomogram based on the log odds of negative lymph node/T stage can predict the prognosis of patients with colorectal cancer: a retrospective study based on SEER database and external validation in China.
BMJ Open
December 2024
Department of Gastroenterology, The Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Dongguan, China
Objectives: This study investigated the prognostic role of log odds of negative lymph node/T stage (LONT) and established a nomogram based on LONT to predict the prognosis in colorectal cancer (CRC) patients.
Design: A retrospective cohort study.
Setting And Participants: We enrolled 80 518 CRC patients from the Surveillance, Epidemiology and End Results database between 2010 and 2015.
Impact of different staging methods of lymph nodes metastases on prognosis in advanced hypopharyngeal squamous cell carcinoma.
J Craniomaxillofac Surg
January 2025
Department of Otorhinolaryngology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, China; Department of Otorhinolaryngology, Kashi Prefecture Second People's Hospital, Xinjiang Uygur Autonomous Region, Xinjiang, 844000, China. Electronic address:
Background: Lymph node ratio (LNR), log odds of positive lymph nodes (LODDS), and the number of postoperative lymph node staging (pN) are prognostic indicators of various cancers. However, the prognostic values of these indicators remain unclear in hypopharyngeal squamous cell carcinoma (HPSCC). This study's primary objective was to investigate the predictive value of LNR, LODDS, and pN for advanced HPSCC, and the secondary objective was to compare which of the values had the best predictive value for advanced HPSCC.
View Article and Find Full Text PDFRecursive partitioning staging system based on the log odds of the negative lymph node/T stage ratio in colon mucinous adenocarcinoma.
Front Immunol
January 2025
Department of Colorectal Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Background: This study aimed to investigate the prognostic significance of the log odds of negative lymph nodes/T stage ratio (LONT) and develop an efficient prognostic staging system using LONT in patients with colon mucinous adenocarcinoma (MAC).
Methods: This study included 5,236 patients diagnosed with colon MAC obtained from the Surveillance, Epidemiology, and End Results database. The Kaplan-Meier method, subgroup analysis, receiver operating characteristic (ROC) curve, and Cox proportional hazard regression model were used to determine the clinical outcomes.
Identification of confounders and estimating the causal effect of place of birth on age-specific childhood vaccination.
BMC Med Inform Decis Mak
December 2024
School of Mathematics, Statistics & Computer Science, University of KwaZulu Natal, Durban, South Africa.
Background: In causal analyses, some third factor may distort the relationship between the exposure and the outcome variables under study, which gives spurious results. In this case, treatment groups and control groups that receive and do not receive the exposure are different from one another in some other essential variables, called confounders.
Method: Place of birth was used as exposure variable and age-specific childhood vaccination status was used as outcome variables.
Review: Systematic review and meta-analysis - financial incentives increase engagement with parenting programs for disruptive behavior problems.
Child Adolesc Ment Health
December 2024
Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Background: To evaluate the effect of financial incentives on engagement in parenting programs for disruptive behavior disorders, as well as effect on child behavior. As a secondary aim, demographic differences were investigated as effect modifiers.
Methods: We searched PubMed, CINAHL, Sociological Abstracts, Cochrane Trials, and PsycINFO for randomized controlled trials and quasi experimental studies offering parents a financial incentive for engagement with parenting programs targeting disruptive behavior in children aged under 18, vs no incentive.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!