Generation of an array of optical vortices (OVs) with fractional charges under the condition of acousto-optic Bragg diffraction is revealed experimentally. The OVs emerge in a wide diffracted optical beam due to reflection from a thick acousto-optic grating that contains bifurcated fringes of acoustic waves (AWs). Changes in the AW frequency lead to deflection of the wide optical beam containing the OV array. The OVs preserve their spatial positions only in the narrow AW frequency range, while larger changes in the frequency impose their movement out from the beam aperture, with appearance of the other OVs in the other places of the beam cross section.
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http://dx.doi.org/10.1364/AO.57.010284 | DOI Listing |
Cureus
December 2024
Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, USA.
Purpose Low-dose total skin electron beam therapy (LD-TSEBT) has recently gained popularity in treating mycosis fungoides (MF) due to its reduced toxicity and favorable response rates. Combining accelerated LD-TSEBT with the modified Stanford technique (mST), a condensed cycling approach, offers a promising and convenient option. However, in vivo dosimetry data confirming the effectiveness of this approach is limited.
View Article and Find Full Text PDFAnal Chem
January 2025
School of Optoelectronic Engineering and Instrumentation Science, Dalian University of Technology, Dalian, Liaoning 116024, China.
A linear spot-type multipass cell-enhanced fiber-optic photoacoustic gas microprobe is proposed. To further reduce the volume of the gas chamber and enhance the photoacoustic signal, we designed the cross section of the photoacoustic tube as a slit with a height of 10 mm and a width of 1.5 mm.
View Article and Find Full Text PDFRev Sci Instrum
January 2025
Department of Micro Engineering, Graduate School of Engineering, Kyoto University, Kyotodaigaku-Katsura C3, Nishikyo-ku, Kyoto 615-8540, Japan.
The measurement of thermal conductivities of anisotropic materials and atomically thin films is pivotal for the thermal design of next-generation electronic devices. Frequency-domain thermoreflectance (FDTR) is a pump-probe technique that is known for its accurate and straightforward approach to determining thermal conductivity and stands out as one of the most effective methodologies. Existing research has focused on advancing a measurement system that incorporates beam-offset FDTR.
View Article and Find Full Text PDFJ Med Life
November 2024
Biophysics and Cellular Biotechnology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Optical tweezers, which leverage the forces exerted by radiation pressure, have emerged as a pivotal technique for precisely manipulating and analyzing microscopic particles. Since Arthur Ashkin's ground-breaking work in the 1970s and the subsequent development of the single-beam optical trap in 1986, the capabilities of optical tweezers have expanded significantly, enabling the intricate manipulation of biological specimens at the micro- and nanoscale. This review elucidates the foundational principles of optical trapping and their extensive applications in the biomedical sciences.
View Article and Find Full Text PDFStargardt disease is a currently untreatable, inherited neurodegenerative disease that leads to macular degeneration and blindness due to loss-of-function mutations in the ABCA4 gene. We have designed a dual adeno-associated viral vector encoding a split-intein adenine base editor to correct the most common mutation in ABCA4 (c.5882G>A, p.
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