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True Left-Sided Gallbladder: A Case Report of Rare Incidental Findings During Cholecystectomy in a Jordanian Patient.
Cureus
December 2024
General Surgery, Jordanian Royal Medical Services, Amman, JOR.
The biliary system exhibits significant anatomical variations, which pose challenges for most surgeons during cholecystectomy. Among these variations, a true left-sided gallbladder (LSG) is an uncommon finding. In such cases, the gallbladder is located to the left of the round ligament.
View Article and Find Full Text PDFImpact of metabolic-associated fatty liver disease on the cholesterol efflux capacity of high-density lipoproteins in adolescents with type 2 diabetes.
Front Pediatr
December 2024
Department of Endocrinology, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Context: Type 2 diabetes (DM2) is an emerging disease in the pediatric population. DM2 is associated with metabolic-associated fatty liver disease (MAFLD). High-density lipoproteins (HDLs) are lipoproteins that are believed to have atheroprotective properties that reduce the risk of cardiovascular disease (CVD).
View Article and Find Full Text PDFWho will benefit from vorasidenib? Review of data from the literature and open questions.
Neurooncol Pract
February 2025
Department of Neurological Surgery, University of California San Francisco and Weill Institute for Neurosciences, San Francisco, California, USA.
The clinical efficacy of isocitrate dehydrogenase (IDH) inhibitors in the treatment of patients with grade 2 IDH-mutant (mIDH) gliomas is a significant therapeutic advancement in neuro-oncology. It expands treatment options beyond traditional radiation therapy and cytotoxic chemotherapy, which may lead to significant long-term neurotoxic effects while extending patient survival. The INDIGO study demonstrated that vorasidenib, a pan-mIDH inhibitor, improved progression-free survival for patients with grade 2 mIDH gliomas following surgical resection or biopsy compared to placebo and was well tolerated.
View Article and Find Full Text PDFChallenges and Opportunities in Examining and Addressing Intersectional Stigma and Health.
Focus (Am Psychiatr Publ)
January 2025
Department of Health Care Organization and Policy, School of Public Health, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35294, USA (Turan); Department of Neurology, Johns Hopkins Hospital, Baltimore, MD, USA (Elafros); Factor-Inwentash Faculty of Social Work, Toronto, ON, Canada (Logie); Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada (Logie); Department of Public Health & Prevention Sciences, Baldwin Wallace University, Berea, OH, USA (Banik); Department of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA (Turan and Crockett); Department of Sociology, Indiana University, Bloomington, IN, USA (Pescosolido); Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA (Murray).
Background: 'Intersectional stigma' is a concept that has emerged to characterize the convergence of multiple stigmatized identities within a person or group, and to address their joint effects on health and wellbeing. While enquiry into the intersections of race, class, and gender serves as the historical and theoretical basis for intersectional stigma, there is little consensus on how best to characterize and analyze intersectional stigma, or on how to design interventions to address this complex phenomenon. The purpose of this paper is to highlight existing intersectional stigma literature, identify gaps in our methods for studying and addressing intersectional stigma, provide examples illustrating promising analytical approaches, and elucidate priorities for future health research.
View Article and Find Full Text PDFWhat Are the Barriers, Facilitators and Interventions Targeting Help-Seeking Behaviours for Common Mental Health Problems in Adolescents? A Systematic Review.
Focus (Am Psychiatr Publ)
January 2025
Child and Adolescent Mental Health Service, Children's Hospital Dr. Roberto del Río, Santiago, Chile (Velasco); Public Health School, Faculty of Medicine, University of Chile, Santiago, Chile (Cruz); División of Psychiatry, University College London, London, UK (Billings, Rowe); Camden and Islington Mental Health Foundation Trust, London, UK (Jimenez).
Background: Increasing rates of mental health problems among adolescents are of concern. Teens who are most in need of mental health attention are reluctant to seek help. A better understanding of the help-seeking in this population is needed to overcome this gap.
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