Survival kinetics of Salmonella enterica have been previously studied using an inoculum cocktail composed of different strains that have been associated with low-moisture foods. Here, we report the closed genome sequences of five strains of Salmonella enterica that are commonly used in these storage studies.
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http://dx.doi.org/10.1128/MRA.01588-18 | DOI Listing |
Vet Med Sci
January 2025
Department of Animal Nutrition and Nutritional Disease, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Turkey.
Photodynamic inactivation (PDI) is a new and promising strategy for eliminating foodborne pathogenic bacteria in food preservation, reducing associated health risks for consumers. This study aimed to develop an innovative PDI-based system to inactivate Salmonella Enteritidis PT4 on eggshells. The system includes 405 nm light-emitting diodes (LEDs) and the application of curcumin or carvacrol as photosensitizers.
View Article and Find Full Text PDFWorld J Microbiol Biotechnol
January 2025
Microbiology, Botany Department, Faculty of Agriculture, Tanta University, Tanta City, 31527, Egypt.
Bee venom (BV) represents a promising natural alternative to conventional antibiotics, particularly significant given its broad-spectrum antimicrobial activity and potential to address the growing challenge of antimicrobial resistance. The prevalence of antimicrobial-resistant microorganisms (AMR) is a global burden that affects human health and the economies of different countries. As a result, several scientific communities around the world are searching for safe alternatives to antibiotics.
View Article and Find Full Text PDFMikrochim Acta
January 2025
Department of Biotechnology and Bioengineering, Chonnam National University, Gwangju, 61186, Republic of Korea.
The global healthcare market increasingly demands affordable molecular diagnostics for field testing. To address this need, we introduce a lab-on-paper (LOP) platform that integrates isothermal amplification with a specially designed paper strip for molecular testing through an automated microfluidics process. The LOP system is engineered for rapid, cost-effective, and highly sensitive detection, using USB-powered thermal management and a wax valve mechanism.
View Article and Find Full Text PDFFood Funct
January 2025
State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine Jilin University, Center of Infectious Diseases and Pathogen Biology, Department of Infectious Diseases, First Hospital of Jilin University, Changchun, China.
serovar Typhimurium (STM) causes severe colitis, necessitating the development of effective drugs. Here, the dockings of limonin with the STM T3SS-1 virulence factor SopB or SopE2 showed strong binding activity and was verified by CETSA and DARTS assays . Limonin inhibited the enzyme activities and expression of SopB and SopE2 .
View Article and Find Full Text PDFElife
January 2025
Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.
Trained immunity (TI) is the process wherein innate immune cells gain functional memory upon exposure to specific ligands or pathogens, leading to augmented inflammatory responses and pathogen clearance upon secondary exposure. While the differentiation of hematopoietic stem cells (HSCs) and reprogramming of bone marrow (BM) progenitors are well-established mechanisms underpinning durable TI protection, remodeling of the cellular architecture within the tissue during TI remains underexplored. Here, we study the effects of peritoneal Bacillus Calmette-Guérin (BCG) administration to find TI-mediated protection in the spleen against a subsequent heterologous infection by the Gram-negative pathogen Typhimurium (.
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