Postural control requires constant and subconscious postural sway to manage balance and achieve postural stability. These movements of regulation are based in particular on cutaneous plantar information. The foot constitutes a functional whole that participates in the mechanisms of postural control and regulation. It represents the direct interface between the body and the ground during quiet standing, and plantar cutaneous information contributes to postural control. Upright balance mechanically depends on the gravitational torque produced by the forces of gravity and reaction of the ground. In this context, the foot behaves like a sensory system for postural regulation whose objective is to maintain a state of stability within a changing and constraining environment. There is a relation between balance improvement and the facilitation of sensory feedback related to the activation of the plantar cutaneous mechanoreceptors. From a clinical point of view, the application of additional tactile cues may have therapeutic benefits in relation to fall prevention, or to improve specific types of chronic pain.
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http://dx.doi.org/10.1016/j.neucli.2018.12.006 | DOI Listing |
SAGE Open Med Case Rep
December 2024
Division of Dermatology, Department of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
Stevens-Johnson syndrome and drug reaction with eosinophilia and systemic symptoms are severe cutaneous adverse reactions to drugs that are generally considered distinct entities. In addition to identifying the offending medication, distinguishing between these diagnoses is important, as they have differing treatment regimens and prognoses. Distinction between severe cutaneous adverse reactions, particularly in the early stages of disease, can be difficult, and overlapping conditions have been reported in the literature.
View Article and Find Full Text PDFArch Dermatol Res
December 2024
Department of Dermatology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Several studies have looked into the effectiveness of bleomycin treatment for warts using various injection methods, such as intralesional injection, multiple puncture technique, jet injection, and moonlet needle prick method, in various concentrations and doses. However, injection methods have been linked to acute pain and bleeding. The purpose of this study is to examine the efficacy of microneedling combination with topical bleomycin and cryotherapy in the treatment of resistant warts on the hands and feet.
View Article and Find Full Text PDFJ Exp Clin Cancer Res
December 2024
The Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Background: Acral melanoma (AM) is an aggressive melanoma variant that arises from palmar, plantar, and nail unit melanocytes. Compared to non-acral cutaneous melanoma (CM), AM is biologically distinct, has an equal incidence across genetic ancestries, typically presents in advanced stage disease, is less responsive to therapy, and has an overall worse prognosis.
Methods: An independent analysis of published sequencing data was performed to evaluate the frequency of receptor tyrosine kinase (RTK) ligands and adapter protein gene variants and expression.
Viruses
November 2024
Department of Biomedical Sciences, University of West Attica, Campus I, 12243 Athens, Greece.
Sci Rep
November 2024
Department of Dermatology, Pusan National University Yangsan Hospital, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, 50612, Republic of Korea.
The utility of dermoscopy for the diagnosis of cutaneous warts is well known. However, its role in predicting the outcome of cryotherapy for cutaneous warts remains unexplored. To identify dermoscopic features predicting treatment responses in cryotherapy for cutaneous warts.
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