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Multimodal Pain Recognition in Postoperative Patients: Machine Learning Approach.
JMIR Form Res
January 2025
Department of Computer Science, University of California, Irvine, Irvine, CA, United States.
Background: Acute pain management is critical in postoperative care, especially in vulnerable patient populations that may be unable to self-report pain levels effectively. Current methods of pain assessment often rely on subjective patient reports or behavioral pain observation tools, which can lead to inconsistencies in pain management. Multimodal pain assessment, integrating physiological and behavioral data, presents an opportunity to create more objective and accurate pain measurement systems.
View Article and Find Full Text PDFMITIGATING OVER-SATURATED FLUORESCENCE IMAGES THROUGH A SEMI-SUPERVISED GENERATIVE ADVERSARIAL NETWORK.
Proc IEEE Int Symp Biomed Imaging
May 2024
Department of Electrical and Computer Engineering, Nashville, TN, USA.
Multiplex immunofluorescence (MxIF) imaging is a critical tool in biomedical research, offering detailed insights into cell composition and spatial context. As an example, DAPI staining identifies cell nuclei, while CD20 staining helps segment cell membranes in MxIF. However, a persistent challenge in MxIF is saturation artifacts, which hinder single-cell level analysis in areas with over-saturated pixels.
View Article and Find Full Text PDFChanges in microcirculation variables in an acute endotoxaemic equine model.
Equine Vet J
January 2025
Clinic for Horses, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Background: Microcirculation is the essential link between macrocirculation and cellular metabolism.
Objectives: To test our hypotheses that microcirculation variables will show a heterogeneous flow pattern during experimental endotoxaemia, and that fluid therapy and noradrenaline (NA) infusion will normalise altered microcirculation variables.
Study Design: In vivo experiments.
Impact of ultrasound settings on lung vertical artefacts: an observational study in mechanically ventilated patients.
ERJ Open Res
January 2025
Critical Care Department, Hospital Garcia de Orta EPE, Almada, Portugal.
Introduction: The number of vertical artefacts (VAs) in lung ultrasound (LUS) impacts patients' clinical management. This study aimed to demonstrate the influence of ultrasound settings on the number of VAs in patients under invasive mechanical ventilation (IMV).
Methods: Patients under IMV were recruited for LUS, including three breathing cycles with a motionless curvilinear probe on the thoracic region with the most VAs.
Exploring early Acheulian technological decision-making: A controlled experimental approach to raw material selection for percussive artifacts in Melka Wakena, Ethiopia.
PLoS One
January 2025
Department of Prehistory, Institute of Archaeology, Hebrew University of Jerusalem, Jerusalem, Israel.
The evolution of human behaviour is marked by key decision-making processes reflected in technological variability in the early archaeological record. As part of the technological system, differences in raw material quality directly affect the way that humans produce, design and use stone tools. The selection, procurement and use of various raw materials requires decision-making to evaluate multiple factors such as suitability to produce and design tools, but also the materials' efficiency and durability in performing a given task.
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