Prostate segmentation in Magnetic Resonance (MR) Images is a significant yet challenging task for prostate cancer treatment. Most of the existing works attempted to design a global classifier for all MR images, which neglect the discrepancy of images across different patients. To this end, we propose a novel transfer approach for prostate segmentation in MR images. Firstly, an image-specific classifier is built for each training image. Secondly, a pair of dictionaries and a mapping matrix are jointly obtained by a novel Semi-Coupled Dictionary Transfer Learning (SCDTL). Finally, the classifiers on the source domain could be selectively transferred to the target domain ( testing images) by the dictionaries and the mapping matrix. The evaluation demonstrates that our approach has a competitive performance compared with the state-of-the-art transfer learning methods. Moreover, the proposed transfer approach outperforms the conventional deep neural network based method.
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http://dx.doi.org/10.1109/ICASSP.2018.8461716 | DOI Listing |
Pharmaceutics
January 2025
Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, Arak 38156-8-8349, Iran.
In the 21st century, thanks to advances in biotechnology and developing pharmaceutical technology, significant progress is being made in effective drug design. Drug targeting aims to ensure that the drug acts only in the pathological area; it is defined as the ability to accumulate selectively and quantitatively in the target tissue or organ, regardless of the chemical structure of the active drug substance and the method of administration. With drug targeting, conventional, biotechnological and gene-derived drugs target the body's organs, tissues, and cells that can be selectively transported to specific regions.
View Article and Find Full Text PDFPharmaceutics
December 2024
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai 400056, Maharashtra, India.
Liposome-based drug delivery technologies have showed potential in enhancing medication safety and efficacy. Innovative drug loading and release mechanisms highlighted in this review of next-generation liposomal formulations. Due to poor drug release kinetics and loading capacity, conventional liposomes have limited clinical use.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Kurchatov Genomics Center, Institute of Cytology and Genetics SB RAS, Lavrentiev Av. 10, 630090 Novosibirsk, Russia.
Soybean () is a leguminous plant with a broad range of applications, particularly in agriculture and food production, where its seed composition-especially oil and protein content-is highly valued. Improving these traits is a primary focus of soybean breeding programs. In this study, we conducted a genome-wide association study (GWAS) to identify genetic loci linked to oil and protein content in seeds, using imputed genotype data for 180 Eurasian soybean varieties and the novel "genotypic twins" approach.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Faculty of Mechanics, University Politehnica of Timisoara, Piata Victoriei 2, 300006 Timisoara, Romania.
This study investigated silicone composites with distributed boron nitride platelets and carbon microfibers that are oriented electrically. The process involved homogenizing and dispersing nano/microparticles in the liquid polymer, aligning the particles with DC and AC electric fields, and curing the composite with IR radiation to trap particles within chains. This innovative concept utilized two fields to align particles, improving the even distribution of carbon microfibers among BN in the chains.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Research School of Chemical and Biomedical Technologies, Tomsk Polytechnic University, Lenin Ave. 30, 634050 Tomsk, Russia.
Laser reduction of graphene oxide (GO) is a promising approach for achieving flexible, robust, and electrically conductive graphene/polymer composites. Resulting composite materials show significant technological potential for energy storage, sensing, and bioelectronics. However, in the case of insulating polymers, the properties of electrodes show severely limited performance.
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