EuroIntervention
Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Published: October 2019
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http://dx.doi.org/10.4244/EIJ-D-18-01013 | DOI Listing |
Nutrients
February 2025
Center of Investigation in Clinical Nutrition, Université Catholique de Louvain, Rue du Marathon, 3, B-1348 Louvain-la-Neuve, Belgium.
The global prevalence of mental health disorders, particularly anxiety and depression, has increased significantly, with rates further elevated by the COVID-19 pandemic. Conventional pharmacological treatments, while effective, often lead to side effects that can impact patient adherence and quality of life. This has driven interest in safer, natural adjunctive therapies.
View Article and Find Full Text PDFFoods
February 2025
College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China.
Adequate protein consumption is essential for optimal physical fitness and enhancing athletic performance. This study explored the impact of BC99 on protein-supplemented male fatigued mice, examining aspects such as protein digestion, exercise endurance, fatigue-related biochemistry, oxidative stress, and gut microbiota alterations. Results indicate that the synergistic effect of probiotics and protein significantly boosts the activity of protein-digesting enzymes, enhances protein absorption, and reduces serum levels of urea nitrogen, lactate, lactate dehydrogenase, creatine kinase, malondialdehyde, and the inflammatory cytokines interleukin-1β and interleukin-6 in skeletal muscle.
View Article and Find Full Text PDFCancers (Basel)
March 2025
Surgical Department of Peritoneal Surface Malignancy Program, EUROMEDICA Kyanous Stavros, 54636 Thessaloniki, Greece.
Hyperthermic intraperitoneal chemotherapy (HIPEC) was revealed as a promising adjunct to cytoreductive surgery (CRS) in the treatment of advanced epithelial ovarian cancer (EOC). This review evaluated the impact HIPEC had on survival outcomes, recurrence patterns and safety in patients that underwent HIPEC in conjunction with interval and secondary CRS for advanced and recurrent ovarian cancer. A thorough search was conducted using PubMed, Scopus, Cochrane Library, and Google Scholar to identify relevant studies published until 1 January 2025.
View Article and Find Full Text PDFCancers (Basel)
February 2025
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090 Milan, Italy.
Colorectal cancer (CRC) prevention depends on effective colonoscopy; yet variability in adenoma detection rates (ADRs) and missed lesions remain significant hurdles. Artificial intelligence-powered computer-aided detection (CADe) systems offer promising advancements in enhancing polyp detection. This review examines the role of CADe in improving ADR and reducing adenoma miss rates (AMRs) while addressing its broader clinical implications.
View Article and Find Full Text PDFDrug Saf
March 2025
Veterans Administration (VA) Center for the Study of Healthcare Innovation, Implementation, and Policy, VA Greater los Angeles Healthcare System, Los Angeles, USA.
Background: Significant methodological shortcomings have been documented to date in risk minimisation program evaluations for medicinal products, including overreliance on survey methods alone. Recently updated guidances from the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) recommend the use of frameworks and mixed methods designs to improve the rigor of these assessments.
Objective: The purpose of this paper was to exemplify how a mixed methods approach, guided by an implementation science framework, can be used to design the evaluation of a risk minimisation program.
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