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http://dx.doi.org/10.1111/head.13474DOI Listing

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Article Synopsis
  • Tuberculosis (TB) is a significant global health issue, particularly impacting immunocompromised patients like those with HIV, making them more susceptible to opportunistic infections and poor outcomes, especially with central nervous system (CNS) involvement.
  • CNS TB can present as tuberculous meningitis (TBM), localized tuberculomas, or spinal infections, with TBM being the most common and serious form, leading to high morbidity and mortality.
  • A case describes a 61-year-old male with HIV presenting with altered consciousness and other neurological symptoms; testing revealed abnormal cerebrospinal fluid and a positive TB test, prompting immediate treatment with antituberculous medications and steroids due to his deteriorating condition.
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Lumbar puncture (LP) is recommended in patients with thunderclap headache and negative computed tomography to rule out spontaneous subarachnoid haemorrhage (SAH). Blood contamination of cerebrospinal fluid (CSF) due to traumatic LP poses a diagnostic dilemma. Therefore, routine CSF parameters were investigated to distinguish between SAH and a traumatic LP.

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Objective: The two most common causes of eosinophilic meningitis (EOM) are the parasites: and . This study aimed to evaluate whether clinical factors can predict either neuroangiostrongyliasis or gnathostomiasis in EOM patients.

Materials And Methods: We included reports of patients with eosinophils in the CSF and either serological or pathological diagnosis of neuroangiostrongyliasis or gnathostomiasis published in 2014 or earlier and available on PubMed.

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A 71-year-old man had sustained intermittent ptosis and double vision for 2 weeks. Neurological examination found unilateral oculomotor nerve (CN III) paresis manifesting as limitations of gaze, ptosis, and mydriasis. Neither headache nor any other cranial neuropathy was noted.

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