Bacteriophages in Dentistry-State of the Art and Perspectives.

Dent J (Basel)

Department of Morphological Sciences, Federal University of Rio Grande do Sul-UFRGS, Porto Alegre 90040-060, Brazil.

Published: January 2019

AI Article Synopsis

  • Bacteriophages, discovered in 1915, can target and kill bacteria but fell out of favor with the rise of antibiotics.
  • Their application in dentistry remains scarce, prompting the authors to review relevant studies on their structure, effectiveness, and potential use in oral health.
  • The review also discusses how bacteriophages can combat dental biofilm and examines the pros and cons of phage therapy in dental practices.

Article Abstract

Bacteriophages, viruses capable of killing bacteria, were discovered in 1915, but the interest in their study has been limited since the advent of antibiotics. Their use in dentistry is still very limited. The authors reviewed studies about bacteriophage structure, mode of action, uses in oral health, and possible future uses in dentistry associated with their possible action over biofilm, as well as the advantages and limitations of phage therapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473837PMC
http://dx.doi.org/10.3390/dj7010006DOI Listing

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Article Synopsis
  • Bacteriophages, discovered in 1915, can target and kill bacteria but fell out of favor with the rise of antibiotics.
  • Their application in dentistry remains scarce, prompting the authors to review relevant studies on their structure, effectiveness, and potential use in oral health.
  • The review also discusses how bacteriophages can combat dental biofilm and examines the pros and cons of phage therapy in dental practices.
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