is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. With increased travel and emigration to developed countries, infection is becoming more common in nonendemic areas. Although the majority of individuals infected with remain asymptomatic, some present with amoebic colitis and disseminated disease. As more is learned about its pathogenesis and the host's immune response, the potential for developing a vaccine holds promise. This narrative review outlines the current knowledge regarding and and insight in the development of a vaccine.
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| http://dx.doi.org/10.1155/2018/4601420 | DOI Listing |
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Adaptive approach to diagnosis of amebic liver abscess in non-endemic areas.
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Entamoeba histolytica infections range from asymptomatic intestinal amebiasis to more severe syndromes like invasive colitis or hepatic abscess. While diagnostic tests available for assessing these infections have evolved, the optimal use of newer diagnostics like enteric multiplex Polymerase Chain Reaction (PCR) panels has not been fully established. Here we describe the case of a 34-year-old male with an amebic liver abscess (ALA) that was diagnosed via multiplex Gastrointestinal (GI) PCR panel on formed stool and subsequently confirmed by testing liver abscess fluid (off-label) on the same multiplex GI PCR panel leading to rapid diagnosis and targeted treatment modification with excellent outcome.
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Objective: In the study, various complaints such as gastrointestinal complaints such as diarrhea, constipation, abdominal pain, nausea and vomiting, weight loss, night urination, itching around the anus, malnutrition, malabsorption, anemia, intelligence and developmental delay were reported to University of Health Sciences Türkiye, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Researhc Hospital, Microbiology Laboratory between 2017 and 2022. It was aimed to determine the frequency and distribution of intestinal parasites in patients presenting with clinical symptoms.
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Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional [CINVESTAV-Instituto Politécnico Nacional (IPN)], Mexico City, Mexico.
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