Body mass index and its effects on liver fat content in overweight and obese young adults by proton magnetic resonance spectroscopy technique.

Aim: To assess the association between liver fat content (LFC) and weight status in young adults using proton magnetic resonance spectroscopy (H MRS) technique.

Methods: Seventy-eight healthy young adults, between 19-30 years of age participated in this study. This group was then separated into a control of 39 subjects and an overweight/obese group (OW/OB group) consisting of 39 subjects. Blood biochemical quantity and H MRS was performed for LFC assessment.

Results: LFC was found to be almost three times higher in OW/OB group when compared to the control group. A 48.7% incidence of non-alcoholic fatty liver disease in the OW/OB group was found. Blood biochemical measurements showed statistically higher low-density lipoproteins and triglyceride, lower high-density lipoproteins, and increased glycosylated hemoglobin and fasting glucose in the OW/OB group. Body mass index was a significant independent predictor for LFC after adjusting for age and sex (multiple linear regression; β 0.459, 0.001).

Conclusion: Due to the prevalence of high LFC in the OW/OB group, it can be proposed that weight gain and obesity are sensitive indicators of high hepatic fat content.