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Use of Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography for Nodal Staging in Prostate Cancer and Tailoring of Treatment: A Continuing Conundrum.
Eur Urol
December 2024
Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Trials have shown that prostate-specific membrane antigen (PSMA)-based positron emission tomography/computed tomography (PET/CT) is more accurate than conventional imaging for staging of nodal status in prostate cancer. We discuss the advantages of PSMA PET/CT over current options for nodal staging and highlight the issues that need to be resolved for implementation of this modality in routine practice.
View Article and Find Full Text PDFSystematic Prostate Biopsy Versus Perilesional Sampling: If It Isn't Broke, Why Fix It?
Eur Urol
October 2024
Department of Urology, Universitätsspital Zurich, Zurich, Switzerland.
The 2024 EAU-EANM-ESTRO-ESUR-ISUP-SIOG guidelines for prostate cancer recommend a targeted and perilesional biopsy (TPLBx) strategy for primary diagnosis. In comparison to the classical approach of combined targeted and systematic biopsy, TPLBx may reduce overdiagnosis of insignificant cancers and mitigate the grade shift associated with targeted biopsy.
View Article and Find Full Text PDFEAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer. Part II-2024 Update: Treatment of Relapsing and Metastatic Prostate Cancer.
Eur Urol
August 2024
Department of Urology, Liverpool University Hospitals NHS Trust, Liverpool, UK.
Article Synopsis
- The 2024 guidelines for treating relapsing, metastatic, and castration-resistant prostate cancer (PCa) have been updated by several European medical associations based on new research from 2020 to 2023.
- The updated guidelines include risk stratification to help determine salvage therapy options and highlight new treatment options like ARTAs, PARP inhibitors, and prostate-specific membrane antigen-based therapy.
- These guidelines emphasize the need for a multidisciplinary approach to PCa management and are updated annually to reflect the latest evidence, with the full details available online.
EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer-2024 Update. Part I: Screening, Diagnosis, and Local Treatment with Curative Intent.
Eur Urol
August 2024
Martini-Klinik Prostate Cancer Center, University Hospital Hamburg Eppendorf, Hamburg, Germany; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany; Department of Urology, Koc University Hospital, Istanbul, Turkey.
Background And Objective: The European Association of Urology (EAU)-European Association of Nuclear Medicine (EANM)-European Society for Radiotherapy and Oncology (ESTRO)-European Society of Urogenital Radiology (ESUR)-International Society of Urological Pathology (ISUP)-International Society of Geriatric Oncology (SIOG) guidelines provide recommendations for the management of clinically localised prostate cancer (PCa). This paper aims to present a summary of the 2024 version of the EAU-EANM-ESTRO-ESUR-ISUP-SIOG guidelines on the screening, diagnosis, and treatment of clinically localised PCa.
Methods: The panel performed a literature review of all new data published in English, covering the time frame between May 2020 and 2023.
Comprehensive Geriatric Assessment for Older Women with Early-Stage (Non-Metastatic) Breast Cancer-An Updated Systematic Review of the Literature.
Curr Oncol
September 2023
Nottingham Breast Cancer Research Centre, University of Nottingham, Nottingham NG7 2UH, UK.
Background: A previous systematic review by our team (2012) undertook comprehensive geriatric assessment (CGA) in breast cancer and concluded there was not sufficient evidence to instate CGA as mandatory practice. SIOG/EUSOMA guidelines published in 2021 advocate the use of CGA in breast cancer patients. The aim is to perform an updated systematic review of the literature.
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