Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.007730 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Severe restenosis after stentless treatment with coronary intravascular lithotripsy for calcified nodule lesions: a serial observation with IVUS.
Oxf Med Case Reports
December 2024
Department of Cardiology, Pulmonology, Hypertension & Nephrolgy, Ehime University Graduate School of Medicine, Toon, Japan.
An 82-year-old woman with a history of myocardial infarction presented with worsening effort angina. Coronary angiography (CAG) revealed 75% stenosis in the proximal left anterior descending artery (LAD), with intravascular ultrasound (IVUS) identifying a severe calcified nodule near a previously implanted drug-eluting stent. The lesion was treated with intravascular lithotripsy (IVL) and a drug-coated balloon (DCB), avoiding left main crossover stenting.
View Article and Find Full Text PDFComposite outcomes of drug-coated balloon using in left main bifurcation lesions: a systematic review.
J Geriatr Cardiol
November 2024
Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
Background: Left main coronary bifurcation lesions account for 50% of left main coronary artery disease cases. Although a drug-coated balloon (DCB) has the advantages of immediate release of the drug to the arterial wall and no remaining struts, there is no conclusive evidence to support DCB use.
Methods & Results: We conducted a systematic review in compliance with the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement.
Adhesive polyelectrolyte coating on PLGA particles prolongs drug retention to vessel lesion.
J Control Release
December 2024
MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310058, China; State Key Laboratory of Transvascular Implantation Devices, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou 310009, China. Electronic address:
Restenosis, the re-narrowing of blood vessels after drug-coated balloons (DCBs), remains a major clinical issue. While rapamycin is the current clinical option for preventing restenosis due to its effectiveness and low toxicity, its delivery is limited by poor tissue absorption and rapid clearance, leading to suboptimal drug retention. Here, we developed the adhesive-polyelectrolyte-coated poly(lactic-co-glycolic acid) (PLGA) particles using in-situ UV-triggered polymerization, encapsulating rapamycin.
View Article and Find Full Text PDFPrognostic implications of increased and final quantitative flow ratios in patients treated with drug-coated balloons physiological evaluation after DCB in de novo lesions.
BMC Cardiovasc Disord
December 2024
Beijing Anzhen Hospital, Capital Medical University, Anzhen road No.1, Beijing, China.
Background: Few studies investigated the implications of post-PCI QFR and post-PCI ΔQFR (absolute increase of QFR) in de novo lesions of small coronary disease after drug-coated balloon (DCB).
Objectives: We sought to investigate the prognostic implications of post-PCI QFR and post-PCI ΔQFR in patients who received DCB only.
Methods: Patients were divided according to the optimal cutoff value of the post-PCI QFR and the post-PCI ΔQFR.
Vessel Wall Histologic Changes in a Porcine Model of Arteriovenous Fistula Stenosis Treated with Percutaneous Transluminal Angioplasty.
J Vasc Interv Radiol
December 2024
Vascular and Interventional Radiology Translational Research Lab, Mayo Clinic, Rochester, MN, USA; Department of Radiology, Mayo Clinic, Rochester, MN, USA. Electronic address:
Article Synopsis
- The study investigated how different treatments (balloon angioplasty vs. drug-coated balloons) affect the changes in blood vessel tissues following arteriovenous fistula stenosis in pigs with chronic kidney disease.
- Significant differences in tissue composition were observed, with drug-coated balloons leading to lower neointimal growth and higher endothelial cell counts compared to standard angioplasty.
- The findings suggest that using drug-coated balloons may improve vessel healing and reduce complications over time, as shown by varied immune cell responses and tissue growth patterns.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!