Background: Donation after brain death (DBD) is current praxis in Sweden. Circulatory death is far more common. Donation from patients suffering Out-of-Hospital Cardiac Arrest (OHCA) may have the potential to increase the organ-donor pool. The aim of this study was to describe the potential donor pool and its characteristics if uncontrolled donation after circulatory death (uDCD) were to be implemented in the metropolitan area of Stockholm, Sweden.
Methods: A retrospective analysis was made using data from the Swedish Register for cardiopulmonary resuscitation (SRCR) between 2006 and 2015. Evaluation of potential organ donors was made using selection criteria from five previously published protocols concerning uDCD.
Results: When applying different criteria from each of the five studied protocols in a total of 9,793 cases of OHCA, between 7.5% (n=732) and 1.5% (n=150) of the patients were found to be potential candidates for uDCD. The median age of the sampled uDCD candidates in each protocol was between 48 and 57 years. Male donors were found in 67-76% of all cases.
Conclusion: Although not taking important real-life limitations into account, our results indicate that implementation of a uDCD programme may substantially increase the number of potential organ donors in Stockholm.
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http://dx.doi.org/10.1016/j.resuscitation.2019.01.001 | DOI Listing |
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Aerospace Medical Center, Aerospace Center Hospital, Beijing, China.
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AVIC Beijing Precision Engineering Institute for Aircraft Industry, Aviation Industry Corporation of China, LTD, Beijing, 100076, China.
With the escalating demand for exploration within confined spaces, bionic design methodologies have attracted considerable attention from researchers, primarily due to the intrinsic limitations of human access to hazardous environments. However, contemporary bionic robots primarily attain linear motion through the axial radial deformation of their body segments, thereby lacking the upright functionality that is characteristic of these organisms. In response to the limitations associated with current bionic earthworm robots concerning upright capability and stiffness modulation, we propose an innovative bionic robot that incorporates upright functionality and programmable stiffness.
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Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, SK, Canada.
Bovine tuberculosis (BTB) is an infectious disease of livestock and wildlife species that is caused by pathogenic members of the Mycobacterium tuberculosis complex such as Mycobacterium bovis. Due to the introduction of M. bovis-infected bison in the 1920s, BTB is now endemic in wood bison (Bison bison athabascae) population within the Wood Buffalo National Park (WBNP) in northern Canada.
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This Review evaluates various mouse and rat models of chronic kidney disease (CKD) that result from repeated low-dose cisplatin (RLDC) treatment while also discussing ethical considerations on the topic. Cisplatin can cause nephrotoxicity, and high doses of cisplatin can cause acute kidney injury. The RLDC regimen has been used in the treatment of solid organ cancers and has shown efficacy in reducing the occurrence of acute kidney injury in patients.
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