Controlling dissolved oxygen (DO) at low level can save energy for wastewater treatment plants (WWTPs), but it is easy to induce filamentous sludge bulking. Through establishing the kinetic equation of sludge settleability, ammonia nitrogen (NH -N) load and organic load (food-to-microbe ratio, F/M), the mechanism of the competitive relationship between filamentous and floccular bacteria under low DO was analyzed. The results showed when DO, NH -N load and F/M were in the range of 0.15-0.35 mg/L, 0.035-0.15 d and 0.12-0.42 d, respectively, the mass transfer limitation of organic matter was the main factor determining the dominant growth of filamentous bacteria. When DO, NH -N load and F/M were in the range of 0.35-0.65 mg/L, 0.035-0.065 d and 0.12-0.22 d, respectively, the mass transfer limitation of NH -N was the main factor determining the dominant growth of filamentous bacteria. When DO was low, no matter how NH -N load and F/M changed, the growth of filamentous bacteria was promoted. When DO and F/M were in the range of 0.35-0.65 mg/L and 0.22-0.42 d, respectively, no matter how NH -N load and F/M changed, the growth of filamentous bacteria was inhibited. Therefore, in actual operation, ensuring relatively low DO and high F/M was beneficial for the sludge settleability improvement.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.2166/wst.2018.488 | DOI Listing |
Neurol Sci
November 2024
Department of NEUROFARBA, University of Florence, Largo Piero Palagi, 1, Florence, 50139, Italy.
Objective: Cognitive impairment affects approximately 30% of pediatric onset Multiple Sclerosis (POMS) patients with a negative impact on everyday life. The aim of this study was to evaluate the feasibility and effectiveness of a home-based, computer-assisted training of attention in patients with POMS.
Methods: This was a randomized double-blind study.
BMC Musculoskelet Disord
October 2024
Institute for Biomechanics, BG Unfallklinik Murnau Professor Küntscher Str. 8, 82418, Murnau, Germany.
Introduction: Proximal humerus fractures are usually treated with rigid angle-stable plates or nails. As an alternative, semi-rigid, minimally invasive systems have been developed for supportive fixation. A new system uses this principle with 2.
View Article and Find Full Text PDFClin Pharmacol Ther
January 2025
Neurimmune, Schlieren, Switzerland.
NI006 (aka ALXN2220) is a therapeutic antibody candidate in phase III clinical development for the depletion of amyloid transthyretin (ATTR) in patients with ATTR cardiomyopathy, an infiltrative cardiomyopathy leading to increased left ventricular wall thickness (LVWT). The mode-of-action consists in removal of disease-causing amyloid accumulations by activating phagocytic immune cells, a mechanism without precedent in cardiology. To select a safe and potentially efficacious dose range and treatment duration for a combined first-in-human and proof-of-concept clinical phase Ib study, we developed a mechanistic pharmacokinetic and pharmacodynamic (PK/PD) model that can predict NI006 exposure, its effects on cardiac amyloid load and on LWVT, which is a predictor of heart failure in this disease.
View Article and Find Full Text PDFNat Commun
August 2024
Department of Biochemistry and Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Accurate chromosome segregation during cell division relies on coordinated actions of microtubule (MT)-based motor proteins in the mitotic spindle. Kinesin-14 motors play vital roles in spindle assembly and maintenance by crosslinking antiparallel MTs at the spindle midzone and anchoring spindle MTs' minus ends at the poles. In this study, we investigate the force generation and motility of the Kinesin-14 motors HSET and KlpA.
View Article and Find Full Text PDFBrain Commun
May 2024
Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia.
Up to half of all people with multiple sclerosis experience communication difficulties due to dysarthria, a disorder that impacts the motor aspects of speech production. Dysarthria in multiple sclerosis is linked to cerebellar dysfunction, disease severity and lesion load, but the neuroanatomical substrates of these symptoms remain unclear. In this study, 52 participants with multiple sclerosis and 14 age- and sex-matched healthy controls underwent structural and diffusion MRI, clinical assessment of disease severity and cerebellar dysfunction and a battery of motor speech tasks.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!