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Efficient Semi-Synthesis of Natural δ-( R)-Tocotrienols from a Renewable Vegetal Source. | LitMetric

Efficient Semi-Synthesis of Natural δ-( R)-Tocotrienols from a Renewable Vegetal Source.

J Nat Prod

SONAS, EA921, UNIV Angers , SFR QUASAV, Faculty of Health Sciences, Department of Pharmacy, 16 bd Daviers , 49045 Angers Cedex 01, France.

Published: January 2019

AI Article Synopsis

Article Abstract

Recent studies have highlighted the biological potential of tocotrienols, a vitamin E subfamily. The major natural sources of tocotrienols are complex mixtures requiring particularly challenging purification processes. The present study describes efficient semi-synthetic strategies toward relevant δ-( R)-tocotrienol derivatives, using as a starting material δ-( R)-garcinoic acid, the major vitamin E derivative isolated from Garcinia kola nuts, a renewable vegetal source.

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Source
http://dx.doi.org/10.1021/acs.jnatprod.8b00517DOI Listing

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