AI Article Synopsis
- The study examined apoptosis activity in the thymus, liver, and kidneys of rats at various developmental stages (days 20, 22, 35, 50, 80, 110, and 140) using advanced techniques like alkaline gel electrophoresis and flow cytofluorometry.
- Changes in apoptosis varied with age, peaking on day 20, then dropping to its lowest on days 35-50.
- After this dip, apoptosis levels gradually rose again by day 110, before significantly declining once more by day 140.
Article Abstract
Activity of apoptosis in the thymus, liver, and kidneys on days 20, 22, 35, 50, 80, 110, and 140 of ontogeny was studied in the experiments on rats using the alkaline gel electrophoresis and flow cytofluorometry. Changes in apoptosis intensity depended on animal age. The maximum level of this parameter was observed on day 20 of ontogeny with the following reduction in this parameter to the minimum value on days 35-50. Then it gradually increased up to relatively high levels on day 110 and significantly reduced by day 140.
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| http://dx.doi.org/10.1007/s10517-019-04361-y | DOI Listing |
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