Introduction: The full blood count (FBC) is one of the most commonly requested and useful test in common medical practices. Abnormalities can indicate the presence of many disorders. A correct interpretation is then essential to guide the diagnosis. This study aims to determine the reference ranges for full blood count (FBC) in a population of healthy adults in the city of Marrakech.
Methods: We conducted a study analysis of 500 full blood count (FBC) data from adult donors at the Center for blood transfusion Ibn Tofail in Marrakech. The samples were analyzed using XE-5000 automated hematology system and the results were analyzed using SPSS statistical software.
Results: Reference values obtained: white blood cells 3,9.103/ μl - 10,23.103/ μl (women) and 5,11.103/ μl -9,99.103/ μl (men); neutrophils 1,53.103/ μl - 6,05.103/ μl (women) and 1,56.103/ μl - 5,97.103/ μl (men); lymphocytes 1,28.103/ μl - 3,72.103/ μl (women) and 1,17.103/ μl - 3,69.103/ μl (men); hemoglobin 12,94-14,7g/dl (women) and 11,77-18,17g/dl (men); platelets 132.103/ μl - 384.103/ μl (women) and 140.103/ μl -356.103/ μl (men).
Conclusion: Study data provide preliminary reference ranges for full blood count (FBC) in our study population which could be used to guide the treatment of patients and the interpretation of clinical trial results and which could potentially improve the quality of clinical care provided to patients.
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http://dx.doi.org/10.11604/pamj.2018.30.249.14648 | DOI Listing |
Cytotechnology
April 2025
Department of Genetics, Osmania University, Hyderabad, Telangana State India.
Targeting tumor angiogenesis with safe endogenous protein inhibitors is a promising therapeutic approach despite the plethora of the first line of emerging chemotherapeutic drugs. The extracellular matrix network in the blood vessel basement membrane and growth factors released from endothelial and tumor cells promote the neovascularization which supports the tumor growth. Contrastingly, small cleaved cryptic fragments of the C-terminal non collagenous domains of the same basement membrane display antiangiogenic effect.
View Article and Find Full Text PDFFront Pediatr
January 2025
Division of Neonatology, Department of Pediatrics, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Background: Multisystem inflammatory syndrome in neonates (MIS-N) is a rare condition thought to be associated with prenatal exposure to maternal severe acute respiratory syndrome coronavirus 2 infection. This immune-mediated hyperinflammation has been described in neonates with multiorgan dysfunction, including cardiopulmonary, encephalopathy, coagulopathy, and vascular complications. However, renovascular complications in MIS-N are rare.
View Article and Find Full Text PDFNon-myeloablative hematopoietic cell transplantation (HCT) is a curative option for individuals with sickle cell disease (SCD). Our traditional goal with this approach has been to achieve a state of mixed donor/recipient chimerism. Recently, we reported an increased risk of hematologic malignancies (HMs) in adults with SCD following graft failure or mixed chimerism.
View Article and Find Full Text PDFInt J Nephrol Renovasc Dis
January 2025
Astellas Pharma Singapore Pte. Ltd, Singapore, Singapore.
Introduction: Limited data exist regarding treatment patterns and symptom burden of patients with anemia of chronic kidney disease (CKD) in the Middle East, South Africa, and Türkiye.
Methods: This real-world study explored clinical characteristics, symptom burden, and treatment patterns of patients with anemia of CKD living in the Middle East, South Africa, and Türkiye. Physician and patient perceptions of treatment were captured via cross-sectional surveys; patients' clinical characteristics were recorded by retrospective review of medical records.
Heliyon
January 2025
Laboratory of Molecular Toxicology, Faculty of Nature and Life Sciences, University of Jijel, 18000, Jijel, Algeria.
has been traditionally used in northeastern Algeria for treating gastrointestinal disorders, particularly ulcers. This study aimed to assess the gastroprotective, anti-inflammatory, and antioxidant properties of a crude hydroalcoholic extract derived from the leaves of , as well as its subsequent fractions. The gastroprotective effect was studied in an ethanol-induced ulcer model in mice.
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