AI Article Synopsis

  • Sclerosing angiomatoid nodular transformation (SANT) is a rare benign spleen lesion, highlighted in a case of a middle-aged woman with early breast cancer.
  • The lesion was asymptomatic and diagnosed only after a laparoscopic splenectomy.
  • The case emphasizes that a splenic mass found during cancer follow-ups may not mean metastasis; SANT must be considered in such cases.

Article Abstract

Sclerosing angiomatoid nodular transformation (SANT) of the spleen is an extremely rare benign lesion. We herein report a case of asymptomatic SANT of the spleen in a middle-aged woman with early breast carcinoma and an undiagnosed splenic mass, which was successfully treated by laparoscopic splenectomy and diagnosed postoperatively. We also review the literature on SANT to help make knowledge more accessible when clinicians encounter a splenic tumor. The present case taught us the following lesson: the presence of a splenic lesion during follow-up for malignancy is not always indicative of metastasis. Therefore, SANT should be considered in the differential diagnosis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548910PMC
http://dx.doi.org/10.2169/internalmedicine.1948-18DOI Listing

Publication Analysis

Top Keywords

sclerosing angiomatoid
8
angiomatoid nodular
8
nodular transformation
8
review literature
8
sant spleen
8
transformation spleen
4
spleen lessons
4
lessons rare
4
rare case
4
case review
4

Similar Publications

SANT is a rare, non-lymphoid, benign entity, originating from the red pulp of the spleen. It is characterized by the presence of vascular nodules surrounded by a stroma of collagen fibers. It was introduced as a distinct disease entity by Martel et al in 2004, after the histopathological examination of 25 cases.

View Article and Find Full Text PDF

A rare case of sclerosing angiomatoid nodular transformation of spleen: A case report.

Int J Surg Case Rep

December 2024

Jimma University, Institute of Health, Faculty of Medical Sciences, Department of Biomedical Sciences, Jimma, Ethiopia. Electronic address:

Introduction And Importance: Sclerosing angiomatoid nodular transformation of the spleen is a rare benign vascular lesion arising from red pulp of spleen with unknown etiopathogenesis. It is a non-neoplastic condition that affects the spleen only; not described in other sites except one case reported in adrenal gland. Epidemiologically it has slight female predilection.

View Article and Find Full Text PDF

The spleen is occasionally referred to as the 'forgotten organ' because splenic lesions are less common and encountered rarely compared to pathologies of other abdominal solid organs. Therefore, although well-demonstrated using various abdominal imaging modalities, radiologists tend to be less familiar with splenic diseases, making interpretation challenging. This study aimed to review common and uncommon splenic diseases and illustrate the multimodal imaging (including ultrasonography, CT, MRI, and PET/CT) features of these lesions in correlation with their histopathology.

View Article and Find Full Text PDF

Clinicopathological and molecular genetic insights into EBV-positive inflammatory follicular dendritic cell sarcoma.

Hum Pathol

November 2024

Department of Pathology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, Fujian, China. Electronic address:

Article Synopsis
  • - This study focused on analyzing 12 cases of Epstein-Barr virus (EBV)-positive inflammatory follicular dendritic cell sarcoma (EBV + IFDCS) to understand its clinical and pathological features, which are not fully described.
  • - Patients ranged in age from 21 to 84 years, with a predominance of females, and all were alive at the last follow-up despite some experiencing recurrence or metastasis; various subtypes were identified within the cases.
  • - The study revealed significant differences in marker expressions between EBV + IFDCS and traditional follicular dendritic cell sarcoma (FDCS), along with unique genetic mutations and variations that were observed, contributing to a better understanding of this rare condition
View Article and Find Full Text PDF

Two cases of sclerosing angiomatoid nodular transformation of the spleen.

Dig Liver Dis

November 2024

Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, Jilin, China. Electronic address:

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!