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Placental ischemia during pregnancy induces hypertension, cerebral inflammation, and oxidative stress in dams postpartum.
Hypertens Pregnancy
December 2025
Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX, USA.
Background: Preeclampsia (PE) is characterized as de novo hypertension (HTN) with end-organ damage, especially in the brain. PE is hypothesized to be caused by placental ischemia. PE affects ~5-8% of USA pregnancies and increases the risk for HTN and cerebrovascular diseases (CVD) later in life.
View Article and Find Full Text PDFIncidence and predictors of adverse birth outcomes among women who gave birth at Assosa general hospital, Northwest Ethiopia: a retrospective cohort study.
BMC Pregnancy Childbirth
January 2025
Department of Public Health, College of Health Science, Assosa University, Benishangul-Gumuz region, Assosa Town, Ethiopia.
Background: Adverse birth outcomes are a significant public health problem worldwide, particularly in low- and middle-income countries. Adverse birth outcomes have significant immediate and long-term health consequences for infants and their families. Understanding the determinants of adverse birth outcomes is crucial to effective interventions.
View Article and Find Full Text PDFCOVID-19 status and utilisation of essential maternal and child healthcare services during the pandemic in Ahmedabad, India.
BMC Pregnancy Childbirth
January 2025
Department of Public Health Science, Indian Institute of Public Health Gandhinagar (IIPHG), Gandhinagar, Gujarat, India.
Background: Access to essential healthcare services is pertinent to the achievement of universal health coverage in any nation. The COVID-19 lockdown was used to mitigate the spread of the pandemic. Consequently, there was a reduction in the Utilisation of Basic Healthcare Services (UBHS) in diverse dimensions.
View Article and Find Full Text PDFHow to estimate the probability of a live birth after one or more complete IVF cycles? the development of a novel model in a single-center.
BMC Pregnancy Childbirth
January 2025
Reproductive Center of Shenzhen Zhongshan Obstetrics and Gynecology Hospital Formerly Reproductive Center of Shenzhen Zhongshan Urology Hospital, Shenzhen, Guangdong Province, China.
Objective: To develop a predictive tool in the form of a Nomogram based on the Cox regression model, which incorporates the impact of the length of treatment cycles on the outcome of live birth, to evaluate the probability of infertile couples having a live birth after one or more complete cycles of In Vitro Fertilization (IVF), and to provide patients with a risk assessment that is easy to understand and visualize.
Methods: A retrospective study for establishing a prediction model was conducted in the reproductive center of Shenzhen Zhongshan Obstetrics & Gynecology Hospital (formerly Shenzhen Zhongshan Urology Hospital). A total of 4413 patients who completed ovarian stimulation treatment and reached the trigger were involved.
Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study.
BMC Med Imaging
January 2025
Oxford Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, Level 1, Oxford Heart Centre, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK.
Background: Preterm birth (< 37 weeks' gestation) alters cerebrovascular development due to the premature transition from a foetal to postnatal circulatory system, with potential implications for future cerebrovascular health. This study aims to explore potential differences in the Circle of Willis (CoW), a key arterial ring that perfuses the brain, of healthy adults born preterm.
Methods: A total of 255 participants (108 preterm, 147 full-term) were included in the analysis.
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