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How does live streaming affect tourists' intention - a psychology theory perspective.
Sci Rep
January 2025
Faculty of Hospitality and Tourism Management, Macau University of Science and Technology, Macao, China.
As a novel experiential approach, live streaming at tourist destinations has garnered significant attention and profoundly impacts tourists' travel decisions. This study aims to validate the effects of usefulness, authenticity, and interactivity of destination live streams on the decision-making process of tourists. Grounded in stimulus-organism-response (S-O-R) theory, this research identifies the usefulness, authenticity, and interactivity of destination live streams as the "stimulus," while telepresence and trust as the "organism," with tourists' travel decisions as the "response.
View Article and Find Full Text PDFEvidence of DNA methylation heterogeneity and epipolymorphism in kidney cancer tissue samples.
Oncogene
January 2025
Early Cancer Institute, Cancer Research UK Cambridge Centre, Cambridge Biomedical Campus, Cambridge, UK.
Clear cell renal cell carcinoma (ccRCC) is characterised by significant genetic heterogeneity, which has diagnostic and prognostic implications. Very limited evidence is available regarding DNA methylation heterogeneity. We therefore generate sequence level DNA methylation data on 136 multi-region tumour and normal kidney tissue from 18 ccRCC patients, along with matched whole exome sequencing (85 samples) and gene expression (47 samples) data on a subset of samples.
View Article and Find Full Text PDFInterstitial lung disease (ILD) has shown limited treatment advancements, with minimal exploration of circulating protein biomarkers causally linked to ILD and its subtypes beyond idiopathic pulmonary fibrosis (IPF). In this study, we aimed to identify potential drug targets and circulating protein biomarkers for ILD and its subtypes. We utilized the most recent large-scale plasma protein quantitative trait loci (pQTL) data detected from the antibody-based method and ILD and its subtypes' GWAS data from the updated FinnGen database for Mendelian randomization analysis.
View Article and Find Full Text PDFRole of the International Society of Liquid Biopsy (ISLB) in establishing quality control frameworks for clinical integration.
Crit Rev Oncol Hematol
January 2025
Division of Medical Oncology, The Arthur G. James Comprehensive Cancer Center, Columbus, OH, USA.
Liquid biopsy (LB) has revolutionized molecular pathology, offering non-invasive insights into tumor biology. However, widespread adoption is hindered by a lack of standardized protocols, requiring robust quality control and harmonized workflows. Large-scale studies are needed to establish effective standard operating procedures (SOPs), particularly for circulating tumor DNA (ctDNA) assays tailored to different disease stages.
View Article and Find Full Text PDFExamining the value realization of ecological agricultural products in China: A tripartite evolutionary game analysis.
J Environ Manage
January 2025
School of Economy and Management, Shandong Agricultural University, Taian, 271018, PR China. Electronic address:
Agricultural products are essential for nutrition and food security, particularly in China where agricultural production capacity is growing steadily. Despite the benefits of Ecological Agricultural (EA) products, including environmental protection and enhanced consumer utility, their widespread adoption and maximization of value are impeded by various factors. This study explores the intricate tripartite relationship - government, agribusiness, and consumer, in the value realization of EA products in China by establishing an evolutionary game model.
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