On the interpretation of the hazard ratio in Cox regression.

Biom J

Department of Biostatistics, University of Copenhagen, Copenhagen K, Denmark.

Published: May 2020

We argue that the term "relative risk" should not be used as a synonym for "hazard ratio" and encourage to use the probabilistic index as an alternative effect measure for Cox regression. The probabilistic index is the probability that the event time of an exposed or treated subject exceeds the event time of an unexposed or untreated subject conditional on the other covariates. It arises as a well known and simple transformation of the hazard ratio and nicely reveals the interpretational limitations. We demonstrate how the probabilistic index can be obtained using the R-package Publish.

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Source
http://dx.doi.org/10.1002/bimj.201800255DOI Listing

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