Hydroperoxides derived from marine sources: origin and biological activities.

Appl Microbiol Biotechnol

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow, Russia, 119991.

Published: February 2019

AI Article Synopsis

  • Hydroperoxides are biologically active compounds found in marine environments, characterized by the functional group (R-O-O-H).
  • Research highlights over 80 types of hydroperoxides sourced from various marine organisms, including bacteria, fungi, and algae.
  • These compounds display significant antineoplastic (cancer-fighting), anti-inflammatory, and antiprotozoal properties, with confidence levels ranging from 73% to 94%, depending on their specific source.

Article Abstract

Hydroperoxides are a small and interesting group of biologically active natural marine compounds. All these metabolites contain a group (R-O-O-H). In this mini-review, studies of more than 80 hydroperoxides isolated from bacteria, fungi, algae, and marine invertebrates are described. Hydroperoxides from the red, brown, and green algae exhibit high antineoplastic, anti-inflammatory, and antiprotozoal activity with a confidence of 73 to 94%. Hydroperoxides produced by soft corals showed antineoplastic and antiprotozoal activity with confidence from 81 to 92%. Metabolites derived from sea sponges, mollusks, and other invertebrates showed antineoplastic and antiprotozoal (Plasmodium) activity with confidence from 80 to 90%.

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Source
http://dx.doi.org/10.1007/s00253-018-9560-xDOI Listing

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