Halitosis is a condition that can have negative social impacts. Although common, its prevalence and associated etiological factors have been studied little in the child/adolescent population. The aim of the present study was to associate the occurrence of halitosis with oral etiological factors in children aged 6-12 years. A cross-sectional study was conducted with 150 male and female children and adolescents. The organoleptic test (OT) was used to determine halitosis. All patients and caregivers answered a questionnaire addressing personal data, general health and oral health, including hygiene habits, and received clarifications regarding the procedures to which the children/adolescents would be submitted in a second session. During the second session, the children were clinically evaluated for halitosis using the OT. The bacterial plaque index, coated tongue index, pH, salivary flow and the presence of dental caries were also determined. Differences in the proportions of the factors were compared between groups (with and without halitosis) using the chi-squared test and Fisher's exact test for categorical variables and the non-parametric Mann-Whitney U test for continuous variables. Halitosis was diagnosed in 17.3% of the children and was associated with a fair score on the Simplified Oral Hygiene Index (OR: 3.5; p = 0.008), the non-daily use of tooth floss (OR: 8.7; p = 0.017), percentage of coated tongue (p = 0.005), abnormal salivary flow (OR: 4.2; p < 0.001) and dental caries (OR: 3.8; p = 0.002). No associations with brushing performed by a caregiver or salivary pH were found.
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http://dx.doi.org/10.1088/1752-7163/aafc6f | DOI Listing |
BMC Infect Dis
January 2025
Programa de Pós-graduação em Ciências Farmacêuticas, Escola de Farmácia, Universidade Federal de Ouro Preto, Ouro Preto, Minas Gerais, Brazil.
Background: Human Papillomavirus (HPV) is the most common sexually transmitted lower genital tract infection worldwide and the main etiological factor of cervical cancer (CC). Since 2006, vaccines have been implemented to reduce CC-related morbidity and mortality. This systematic review and meta-analysis aimed to evaluate the prevalence of cervical infections by non-vaccine high-risk HPV (HR-HPV) types in women vaccinated against types 16 and 18.
View Article and Find Full Text PDFHPB (Oxford)
January 2025
Surgical Gastroenterology Unit, Division of General Surgery, University of Cape Town Faculty of Health Sciences and Groote Schuur Hospital, Cape Town, South Africa. Electronic address:
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death globally, particularly in developing countries in Southeast Asia and sub-Saharan Africa (SSA), where chronic hepatitis B virus (HBV) dominates as a major aetiological factor.
Methods: We conducted a retrospective cohort study to quantify the metastatic profile of HCC in a South African patient population managed at a tertiary centre. Demographic, clinical and treatment data were extracted from an institutional registry.
Background: Cerebral venous thrombosis (CVT) is a rare condition in children, and its description remains limited in North Africa. The objective of our study was to describe the clinical, etiological, radiological, therapeutic, and evolutionary characteristics of children with CVT in western Algeria.
Methods: This was a retrospective observational study involving children with CVT.
"Biliary-cast syndrome" ("BCS") is most often encountered in clinical practice as a complication after liver transplantation, there are also described cases of biliary-cast syndrome in patients who did not undergo liver transplantation, isolated cases of "BCS" developing in patients with acute pancreatitis, choledocholithiasis are described in literature. Ischemic damage to bile duct epithelium with development of cholestasis and retrograde biliary tract infection are considered as the main etiological factors. This work presents a clinical case of "Biliary-cast syndrome" in a patient with acute biliary pancreatitis and pulmonary embolism.
View Article and Find Full Text PDFmBio
January 2025
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
In , the causative agent of Lyme disease, differential gene expression is primarily governed by the alternative sigma factor RpoS (σ). Understanding the regulation of RpoS is crucial for elucidating how is maintained throughout its enzootic cycle. Our recent studies have shown that the homolog of Fur/PerR repressor/activator BosR functions as an RNA-binding protein that controls the mRNA stability.
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