AI Article Synopsis
- The 2019 ASCO standards focus on safe handling practices for hazardous drugs, emphasizing the need for clear guidelines in oncology settings.
- An Expert Panel conducted a systematic review of existing literature on handling hazardous drugs, finding no relevant studies on health outcomes from current practices.
- The ASCO panel endorses existing best practices from authoritative bodies while identifying areas needing further research, particularly to evaluate risks in workplace environments and improve safety measures.
Article Abstract
Purpose: To provide 2019 ASCO standards on the safe handling of hazardous drugs.
Methods: An Expert Panel was formed, and a systematic review of the literature on closed system transfer devices was performed to May 2017 using PubMed. The Cochrane Database of Systematic Reviews, PubMed, and Google Scholar were used to search for studies of medical surveillance and external ventilation/health effects of exposure to vapors to November 2017. Available standards were considered for endorsement. Public comments were solicited and considered in preparation of the final manuscript.
Results: The search for primary research found no studies that addressed health outcomes as they relate to the identified interventions of interest. The ASCO Expert Panel endorses the best practices for safe handling of hazardous drugs as issued by the Occupational Safety and Health Administration, US Pharmacopeia Chapter 800, and Oncology Nursing Society with clarifications in four key areas: medical surveillance, closed system transfer devices, external ventilation of containment secondary engineering controls or containment segregated compounding areas, and alternative duties.
Conclusion: The ASCO standards address the need for clear standards concerning safe handling of hazardous oncology drugs. More research is needed in several key areas to quantify the level of risk associated with handling hazardous drugs in current workplace settings where the hierarchy of controls is consistently applied. Additional information is available at www.asco.org/safe-handling-standards .
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1200/JCO.18.01616 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Conflict between sea snakes and humans on the coast of West Bengal and Odisha, India: perception, attitudes and incidents.
Trans R Soc Trop Med Hyg
January 2025
Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai 608502, India.
Background: Snakebite envenoming is a critical medical emergency and significant global public health issue, with India experiencing the highest annual snakebite deaths. Sea snakes in the Indian Ocean pose a severe threat to rural fishermen due to their potent neurotoxins.
Methods: From December 2020 to December 2021, we conducted surveys at 15 fishing ports in East Medinipur, West Bengal, and Balasore, Odisha, India (between 21.
Applying a two-stage generalized synthetic control approach to quantify the heterogeneous health effects of extreme weather events: A 2018 large wildfire in California event as a case study.
Environ Epidemiol
February 2025
Scripps Institution of Oceanography, University of California San Diego, La Jolla, California.
Extreme weather events, including wildfires, are becoming more intense, frequent, and expansive due to climate change, thus increasing negative health outcomes. However, such effects can vary across space, time, and population subgroups, requiring methods that can handle multiple exposed units, account for time-varying confounding, and capture heterogeneous treatment effects. In this article, we proposed an approach based on staggered generalized synthetic control methods to study heterogeneous health effects, using the 2018 California wildfire season as a case study.
View Article and Find Full Text PDFHistorical mining towns: The establishment of 'Soil Planning Areas' for the risk management of contaminated soil.
J Hazard Mater
December 2024
Saxon State Office for Environment, Agriculture and Geology, Halsbrückerstr. 31a, Freiberg 09599, Germany.
Historical mining towns face financial challenges with the proposed Soil Monitoring Law of the European Union, which will require the management of soil contamination, since remediating soil in densely populated towns and cities is challenging. We compared the environmental impact of sulfide ore mining in the urban area of Outokumpu in Finland with that of other European sites, focusing on soil contamination. Soil sampling revealed that mine tailings were historically used in road construction.
View Article and Find Full Text PDFInvestigation of carbon dioxide for scale control in reverse osmosis systems.
J Environ Manage
December 2024
Air Liquide, Brussels, Belgium. Electronic address:
The operation of a reverse osmosis (RO) system is often severely hindered by the deposition of inorganic scales such as calcium carbonate on the membrane surface. Mitigation of this scaling phenomenon requires suitable pH control strategies, with the use of strong mineral acids (e.g.
View Article and Find Full Text PDFCultivated meat microbiological safety considerations and practices.
Compr Rev Food Sci Food Saf
January 2025
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore.
Cultivated meat, produced using cell culture technology, is an alternative to conventional meat production that avoids the risks from enteric pathogens associated with animal slaughter and processing. Cultivated meat therefore has significant theoretical microbiological safety advantages, though limited information is available to validate this. This review discusses sources and vectors of microbial contamination throughout cultivated meat production, introduces industry survey data to evaluate current industry practices for monitoring and mitigating these hazards, and highlights future research needs.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!