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http://dx.doi.org/10.3389/fphys.2018.01777 | DOI Listing |
Future Med Chem
January 2025
Holistic Drug Discovery and Development (H3D) Centre, University of Cape Town, Cape Town, South Africa.
J Rheumatol
January 2025
F. Salvatore, MD, PhD, Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, and "CEINGE - Biotecnologie Avanzate Franco Salvatore," Naples, Italy.
J Alzheimers Dis
January 2025
Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India.
Background: Extracellular signal-regulated kinase 1 (ERK1) belongs to mitogen-activated protein kinases, which are essential for memory formation, cognitive function, and synaptic plasticity. During Alzheimer's disease (AD), ERK1 phosphorylates tau at 15 phosphorylation sites, leading to the formation of neurofibrillary tangles. The overactivation of ERK1 in microglia promotes the release of pro-inflammatory cytokines, which results in neuroinflammation.
View Article and Find Full Text PDFAnaerobe
January 2025
Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL 32610.
The probing of live bacteria via the incorporation of fluorescent D-amino acids (FDAAs) during peptidoglycan synthesis has been shown to be practical for visualizing both gram-positive and gram-negative bacterial species. This study demonstrates the reliability and applications of FDAA labelling for the fluorescent imaging of an obligate anaerobe.
View Article and Find Full Text PDFPlanta
January 2025
School of Molecular and Cellular Biology, Centre for Plant Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, UK.
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