We hypothesized that the slope of relation ventilation to carbon dioxide output (E/CO2-slope) could be predictive already during the very first days after submassive pulmonary embolism (PE) to right ventricular systolic pressure (RV by echocardiography) after 6 months. We evaluated 21 hemodynamically stable patients at admittance, at days 3, 7, 90, and 180 by cardiopulmonary exercise testing and echocardiography. E/CO2-slope (48.4 ± 10.8) decreased within the first week (43.0 ± 9.8 at day 7) and normalized until follow-up at 6 months (35.0 ± 11.3; < 10), p(a-ET)CO remained abnormal between days 1 and 3 (5.0 ± 3.9 to 6.7 ± 5.3 mmHg). RV declined from 41.7 ± 14.3 to 26.3±13.1 mmHg ( < 10) at 6 months. E/CO2-slope (²= 0.27; < .02) and RV (² = 0.28; = .03) at day 7 correlated with RV at 6 months. pCO, pO, D/T were not related to RV after 6 months. RV 6 months after acute PE is positively correlated with the E/CO2-slope at day 7.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300767 | PMC |
| http://dx.doi.org/10.1177/1179548418794155 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Predicting Heart Rate at the Anaerobic Threshold Using a Machine Learning Model Based on a Large-Scale Population Dataset.
J Clin Med
December 2024
Department of Cardiovascular Medicine, Sakakibara Heart Institute, Tokyo 183-0003, Japan.
For effective exercise prescription for patients with cardiovascular disease, it is important to determine the target heart rate at the level of the anaerobic threshold (AT-HR). The AT-HR is mainly determined by cardiopulmonary exercise testing (CPET). The aim of this study is to develop a machine learning (ML) model to predict the AT-HR solely from non-exercise clinical features.
View Article and Find Full Text PDFEffect of Beetroot Juice Supplementation on Aerobic Capacity in Female Athletes: A Randomized Controlled Study.
Nutrients
December 2024
Laboratories and Research Departments, Institute of Innovative Biomedical Technology, 2 Inčukalna Street, LV-1014 Riga, Latvia.
This study addresses the growing interest in nutritional supplements that improve athletic performance in endurance sports. Previous research suggests that nitrates in beetroot juice enhance blood vessel dilation and oxygen delivery to muscles. However, the effects of these nitrates on cardiopulmonary performance in female athletes remain underexplored.
View Article and Find Full Text PDFPrevalence and functional impact of chronotropic incompetence in amyloid cardiomyopathy: a multicentre analysis.
Heart
December 2024
Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Background: Little evidence is available about heart rate (HR) response to exercise as well as its relationship with functional capacity in amyloid cardiomyopathy. Then, in a multicentre cohort of patients with amyloid cardiomyopathy, we investigated the prevalence of chronotropic incompetence (CI) and its relationships with cardiopulmonary exercise testing (CPET) variables.
Methods: Data from 172 outpatients with amyloid cardiomyopathy who performed a maximal CPET and who had no significant rhythm disorders were analysed.
Iron Deficiency and Exercise Capacity in LVAD Patients.
J Card Fail
January 2025
Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
The effects of regular exercise on cognitive and cardiometabolic health in testicular cancer survivors subjected to platinum-based chemotherapy.
Andrology
January 2025
Department of Metabolic Disease Research, Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Background: Platinum-based chemotherapy provides curative treatment to more than 95% of patients with testicular germ cell tumor but it has negative cardiometabolic and neurological effects. Regular exercise can alleviate late chemotherapy-related toxicities. We examined the impact of a 6-month supervised aerobic-strength training on cognitive and cardiometabolic health and residual level of platinum in cancer survivors.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!