Protein circuits reprogram cells.

Nat Chem Biol

Department of Bioengineering, Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA, USA.

Published: February 2019

Two protein circuit systems, split-protease-cleavable orthogonal coiled-coil logic (SPOC logic) and circuits of hacked orthogonal modular proteases (CHOMP), have been developed to permit rapid and logic function-based control of mammalian cellular signaling.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954125PMC
http://dx.doi.org/10.1038/s41589-018-0210-5DOI Listing

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