We analyzed the impact of vancomycin (VAN) combined with adjuvant β-lactam therapy (Combo) on persistent (≥5 days) methicillin-resistant bacteremia versus VAN alone by using pooled data from two previously published observational studies ( = 156). Combo was inversely associated with persistent bacteremia (adjusted odds ratio, 0.460; 95% confidence interval, 0.229 to 0.923). Acute kidney injury was more common with Combo than with VAN (18.9% and 7.6%, respectively; = 0.062).
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395910 | PMC |
| http://dx.doi.org/10.1128/AAC.02211-18 | DOI Listing |
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