Objective: The objective of this study was to identify deficiencies in initiating anti-osteoporotic treatment following a fragility femoral fracture.
Methods: All patients ≥55 years of age treated for a fragility femoral fracture between June 2012 and May 2017 were enrolled. Medications at discharge and at 90 days and 1 year of follow up were analyzed. Patients were classified into 4 groups: Group I did not receive any treatment for osteoporosis; Group II received only calcium and vitamin D; Group III received an anabolic agent, calcium, and vitamin D; and Group IV received bisphosphonates, calcium, and vitamin D.
Results: A total of 167 patients with an average age of 65.81±12.55 years were included. There were 88 (52.7%) males and 79 (47.3%) females. At discharge, 107 patients (64.1%) were not prescribed optimal treatment for osteoporosis, and this reduced to 55 (32.9%) at the 90-day follow up. At 1 year, the number of patients receiving suboptimal treatment was further reduced to 25.74%.
Conclusions: Although the number of patients with fragility fractures receiving insufficient treatment was lower in the present study than in previous reports, increased efforts and coordinated treatment plans initiated by a fracture liaison service should be of high priority.
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http://dx.doi.org/10.1177/0300060518819630 | DOI Listing |
J Endocrinol Invest
January 2025
Section of Endocrinology, Geriatrics and Internal Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Aim: This review aims to overview factors contributing to TAO development and addresses the targeted diagnostic work-up and treatment management in adult thalassemic patients.
Results: Osteoporosis management in Thalassemia is challenging because several factors contributing to its pathogenesis should be considered and controlled starting from child- hood. A multidisciplinary approach is crucial.
Afr J Reprod Health
December 2024
Department of Gynecology, Nanjing General Hospital of Nanjing Military Command, Jiangsu 210000, China.
This study was an original article, mainly aimed to explore the influence of nutritional guidance during pregnancy on nutritional status and pregnancy outcome of pregnant women. Two hundred (200) pregnant women were admitted to the Nanjing General Hospital of Nanjing Military Command from May 2021 to May 2023. They were randomly sub-divided into a control group and an intervention group.
View Article and Find Full Text PDFCalcif Tissue Int
January 2025
Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
Rett syndrome (RS) is a rare neurodevelopmental disorder primarily caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene, responsible for encoding MECP2 which plays a pivotal role in regulating gene expression. The neurological and non-neurological manifestations of RS vary widely in severity depending on the specific mutation type. Bone complications, mostly scoliosis but also osteoporosis, hip displacement, and a high rate of fractures, are among the most prevalent non-neurological comorbidities observed in girls with RS.
View Article and Find Full Text PDFAust Dent J
January 2025
Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Background: Chronic periodontitis is one of the most common inflammatory diseases worldwide. Micronutrients play a significant impact on health and periodontal disease progression. However, there is still a lack of conclusive studies confirming the causal association of micronutrients with chronic periodontitis.
View Article and Find Full Text PDFBr J Nutr
January 2025
Department of Community Medicine, University of Tromsø - The Arctic University of Norway, 9037 Tromsø, Norway.
Colorectal cancer, the third most common cancer globally, causes over 900,000 deaths annually. Although vitamin D is observed to have potential anti-carcinogenic properties, research findings on its preventable effect against colorectal cancer remain inconclusive. Notably, different subsites within the colon and rectum may be associated with distinct risk factors.
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