A novel rhodamine-based Schiff base derivative was obtained via the simple condensation of substituted formyl-1H-pyrrole and rhodamine 6G hydrazone. Fluorescence resonance energy transfer enabled the subsequent use of the derivative as a naked-eye colorimetric and ratiometric fluorescent sensor for Cu in semi-aqueous solution, and the existence of the morpholine group enabled the further application of the sensor in imaging Cu in the lysosomes of HeLa cells.
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| http://dx.doi.org/10.1016/j.saa.2018.12.041 | DOI Listing |
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