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Alzheimers Dement
December 2024
Department of Neurology, University of Colorado Alzheimer's and Cognition Center, and the Linda Crnic Institute for Down Syndrome, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Background: Increasing age is the greatest risk factor for age-associated cognitive decline (AACD) and, especially in females, for developing Alzheimer's disease (AD). Mechanisms underlying this connection are unknown, but neuronal loss and brain atrophy accompany aging and AD and likely contribute to cognitive deficits. There are currently no means to measure neuronal cell death during life and no means to prevent it.
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Alzheimers Dement
December 2024
National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Background: With its rapidly aging population, Japan has been seeing an increase in the concurrent incidence of dementia during heart failure treatment, making disease management difficult. Nevertheless, not much has been uncovered about the actual state of the treatment status and prognosis of heart failure patients with dementia.
Method: At the National Center for Geriatrics and Gerontology, we retrospectively analyzed cases of patients who died of heart failure between 2018 and 2022, who were also complicated with dementia, and whose treatment progress from the initial onset of heart failure to death could be confirmed.
Background: Alzheimer's disease is the sixth most common cause of death in the United States (U.S.), with one in three adults 65 years of age and older dying of the disease each year.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
University of Virginia, Charlottesville, VA, USA.
Background: Seizures are a common co-morbidity of dementia and are associated with accelerated cognitive decline. However, the impact of recurrent versus remote seizures on mortality outcomes in people with dementia (PWD) has not been studied. The purpose of our study is to fill this knowledge gap.
View Article and Find Full Text PDFEnhancing end-of-life care practices on the medicine units: perspectives from nurses and families.
BMJ Open Qual
January 2025
Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Background: Death is a part of life. While most often a sombre event, opportunities exist to optimise the experience both for the dying patient and their loved ones. This is especially true in institutionalised settings, such as acute care hospitals where cure and recovery tend to be paramount.
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