Three new phenylspirodrimanes derivatives named stachybotrysins H and I ( and ) and stachybotrin E (), together with one known compound stachybotrylactam (), were isolated from CGMCC 3.5365. Their structures were determined by extensive NMR data and mass spectroscopic analysis. Compounds and showed inhibitory effect towards potassium channel Kv1.3 with IC values of 13.4 and 10.9 μM, respectively.
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