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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304095 | PMC |
| http://dx.doi.org/10.1136/bmjgh-2018-000846 | DOI Listing |
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Understanding pectin cross-linking in plant cell walls.
Commun Biol
January 2025
Department of Chemistry, University of Warwick, Coventry, UK.
Pectin is a major component of plant cells walls. The extent to which pectin chains crosslink with one another determines crucial properties including cell wall strength, porosity, and the ability of small, biologically significant molecules to access the cell. Despite its importance, significant gaps remain in our comprehension, at the molecular level, of how pectin cross-links influence the mechanical and physical properties of cell walls.
View Article and Find Full Text PDFIntracellular Pocket Conformations Determine Signaling Efficacy through the μ Opioid Receptor.
J Chem Inf Model
January 2025
Department of Chemistry, Illinois Institute of Technology, Chicago, Illinois 60616, United States.
It has been challenging to determine how a ligand that binds to a receptor activates downstream signaling pathways and to predict the strength of signaling. The challenge is compounded by functional selectivity, in which a single ligand binding to a single receptor can activate multiple signaling pathways at different levels. Spectroscopic studies show that in the largest class of cell surface receptors, 7 transmembrane receptors (7TMRs), activation is associated with ligand-induced shifts in the equilibria of intracellular pocket conformations in the absence of transducer proteins.
View Article and Find Full Text PDFShellfish and shorebirds from the East-Asian Australian flyway as bioindicators for unknown per- and polyfluoroalkyl substances using the total oxidizable precursor assay.
J Hazard Mater
January 2025
NILU, Fram Centre, Tromsø 9296, Norway; Norwegian Institute for Public Health, Oslo, Norway. Electronic address:
Per- and polyfluoroalkyl substances (PFAS) have gained significant global attention due to their extensive industrial use and harmful effects on various organisms. Among these, perfluoroalkyl acids (PFAAs) are well-studied, but their diverse precursors remain challenging to monitor. The Total Oxidizable Precursor (TOP) assay offers a powerful approach to converting these precursors into detectable PFAAs.
View Article and Find Full Text PDFInserted-B atoms modulating electronic structure of Pt enhancing hydrogen evolution under Universal-pH.
J Colloid Interface Sci
January 2025
College of Materials Science and Engineering, Fuzhou University, Fuzhou 350108 China. Electronic address:
The development of high-performance electrocatalysts for hydrogen evolution reaction (HER) in different pH conditionsis pivotal in producing green hydrogen, but remains challenging. Herein, we regulate the p-d orbitals hybridization between B and Pt for effective and durable HER at all pH ranges by controlling the inserted B atom. Consequently, the optimized B-doped Pt catalysts with 20 at.
View Article and Find Full Text PDFDaily Supplementation with Protein-Enriched Lacto-Vegetarian Soups and Muscle Health in Community-Dwelling Older Adults: A Randomized Controlled Trial.
J Nutr Health Aging
January 2025
Department of Family Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; Department of Family Medicine, College of Medicine, Tzu Chi University, Hualien, Taiwan; Center for Healthy Longevity, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan. Electronic address:
Background: Dietary protein adequacy is crucial for muscle health in aging individuals, posing a particular challenge for vegetarian seniors. This randomized controlled trial (RCT) investigates the impacts of protein-enriched lacto-vegetarian soup supplementation on body composition, physical performance and muscle strength functional assessment as well as cardiometabolic and inflammatory biomarkers in older adults.
Methods: We enrolled 100 participants ≥65 years at risk for malnutrition (MNA-SF ≤ 11) and at risk for sarcopenia (SARC-F ≥4 or SARC-CalF ≥11) in this RCT.
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