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Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators. | LitMetric
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Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators.

Nikunj M Shukla Michael Chan Tomoko Hayashi Dennis A Carson Howard B Cottam

ACS Med Chem Lett

Moores Cancer Center, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0695, United States.

Published: December 2018

Activation of Toll-like receptors (TLRs) located on immune cells leads to induction of immune responses that can be useful in vaccines for infectious diseases, cancer immunotherapy, and autoimmune diseases. Novel TLR signaling pathway modulators can further enhance the efficacy of TLR ligands.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295859PMC
http://dx.doi.org/10.1021/acsmedchemlett.8b00566DOI Listing

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