Fibrosing processes of connective tissue of unknown etiology affect different anatomical sites either in an isolated or a combined way, masking frequently as tumorous diseases. Clinical manifestations are nonspecific, determined by the site and spread of a process and appear in the form of the syndrome of compression of the adjacent organs. Organ site of a process determines complications and prognosis of disease. Fibromatosis can be diagnosed only in histological investigation. A physician should made aware of a history of traumas surgical interventions, intoxication, fever, increased ESR, dilatation of the aortic arch shadow during x-ray examination, GI tract bleeding, and outline the most effective therapeutic tactics for a patient with mediastinal fibromatosis.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Supraclavicular-median sternotomy approach for a large neurilemmoma invading the thoracic outlet: a case report and review of the literature.
J Cardiothorac Surg
October 2024
Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Road, Jinan, Shandong Province, 250021, China.
Article Synopsis
- Large mediastinum tumors can be challenging to remove due to their size and location near vital organs, making surgical techniques critical for success.
- A case study of a 58-year-old woman illustrates the removal of a large neurilemmoma using a combined supraclavicular and median sternotomy approach, allowing for complete resection without severe complications.
- The findings suggest that this surgical method could be a viable option for dealing with large tumors that invade the thoracic outlet.
[Posterior Mediastinal Desmoid Tumor Suspected to be a Neurogenic Tumor Before Surgery:Report of a Case].
Kyobu Geka
May 2024
Department of Thoracic Surgery, Tokyo Medical Center, Tokyo, Japan.
A man in his 50s who presented an abnormal shadow on chest X-ray was diagnosed with posterior mediastinal tumor that had grown compared to the previous chest X-ray. Computed tomography showed a 5.7×3.
View Article and Find Full Text PDFMediastinal Desmoid Tumor Presents as Lymphadenopathy in Patient with Lymphoma: A Case Report.
Case Rep Oncol
August 2023
Hematology Oncology, Michigan Healthcare Professionals, Royal Oak, MI, USA.
Desmoid tumors are rare mesenchymal neoplasms that are rapidly growing but do not metastasize. We present a case of a 75-year-old man with a history of non-Hodgkin lymphoma in remission incidentally found to have an enlarging internal mammary lymph node on screening CT, subsequently diagnosed as a desmoid tumor via biopsy. The patient was deemed unfit for surgical resection and instead underwent urgent radiation and immunotherapy.
View Article and Find Full Text PDFCase Report: Desmoid fibromatosis in the mediastinum of a 6-month-old toddler, what to do?
Front Surg
January 2023
Department of Internal Medicine, Pathology Service, Hospital Metropolitano, Quito-Ecuador.
Desmoid fibromatosis is a rare, aggressive borderline lesion arising from soft tissues. Treatment will depend on the structures that the tumor has involved. Surgery with negative margins is the recommended strategy as it can usually achieve disease control; however, the tumor's location sometimes does not allow it.
View Article and Find Full Text PDFExpanding the molecular signatures of malignant ossifying fibromyxoid tumours with two novel gene fusions: PHF1::FOXR1 and PHF1::FOXR2.
Histopathology
May 2023
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Aims: Ossifying fibromyxoid tumor (OFMT) is a rare enigmatic tumor of uncertain differentiation that can be classified as typical, atypical, and malignant subtypes based on cellularity, nuclear grade, and mitotic activity. The majority of OFMTs, regardless of the risk of malignancy, harbor genetic translocations. We report two malignant OFMTs, including one with evidence of dedifferentiation, with novel genefusions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!