Background: The differences in treatment outcomes between ultrasound (US)-guided percutaneous microwave ablation (PMWA) and endoscopic thyroidectomy for patients with papillary thyroid microcarcinoma (PTMC) remains unknown.
Methods: An electronic search will be performed for randomized controlled trials or observational studies that reported recurrence and mortality rates in PTMC patients with US-guided PMWA or endoscopic thyroidectomy. Hazard ratios with their 95% confidence intervals will be calculated using fixed- or random-effects models according to heterogeneity.
Results: This study will present the differences in treatment outcomes between US-guided PMWA and endoscopic thyroidectomy for patients with PTMC by pooling the results of individual studies.
Conclusion: The results of this study would provide vigorous evidence in this issue and offer the guidance to both clinical decision-making and future research.
Ethics And Dissemination: Ethical approval is not applicable for this study.
Prospero Registration Number: CRD42018112320.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344203 | PMC |
| http://dx.doi.org/10.1097/MD.0000000000013953 | DOI Listing |
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