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| http://dx.doi.org/10.1264/jsme2.ME17071e | DOI Listing |
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Exploring the therapeutic potential of α-(Phenylselanyl) acetophenone in tumor necrosis Factor-α-Induced depressive-like and hyperalgesic behavior in mice.
Brain Res
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Programa de Pós-Graduação em Bioquímica e Bioprospecção (PPGBBio), Grupo de Pesquisa em Neurobiotecnologia - GPN, Universidade Federal de Pelotas, UFPel, Postal Code 96010-900, Pelotas, RS, Brazil; Programa de Pós-Graduação em Biotecnologia (PPGB), Grupo de Pesquisa em Neurobiotecnologia- GPN, Biotecnologia/Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, Pelotas, RS, Brazil. Electronic address:
Chronic pain and depression exhibit a high comorbidity, are challenging to manage, and their pathophysiology mechanisms are intricated and closely related to the up-regulation of pro-inflammatory response and oxidative stress. Chronic pain and depression often coexist and present significant management challenges. Their underlying pathophysiological mechanisms are complex and closely linked to the up-regulation of pro-inflammatory responses and oxidative stress.
View Article and Find Full Text PDFChronic unpredictable stress exposure disrupts testicular function by modulating germ cell-junctional dynamics and Nrf2/HO-1/IKKβ/NF-κB pathway.
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Male Reproductive Physiology Lab., Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi-221005 (UP), India. Electronic address:
The unpredictable nature of stress complicates understanding its relationship with male infertility. In this study, we investigated testicular germ cell and junctional dynamics in male mice following exposure to chronic unpredictable stress (CUS). Adult Parkes male mice were exposed to CUS for 35 days (one complete spermatogenic cycle), with a random stressor (restraint stress, water deprivation, food deprivation, light flashing, wet bedding, cage shaking, or cage tilting) applied once per day in an intermittent and unpredictable manner to avoid repeating the same stimulus on consecutive days.
View Article and Find Full Text PDFTotal Joint Arthroplasty Patients from Distressed Communities Return to Sports and Physical Activities at Lower Rates.
J Arthroplasty
January 2025
Department of Orthopedic Surgery, Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA.
Background: Patients often desire to participate in sports following total hip arthroplasty (THA) and total knee arthroplasty (TKA), but may be limited functionally and also socioeconomically. The purpose of this study is to investigate the sports participation rates in total joint arthroplasty (TJA) patients based on their Distressed Communities Index (DCI).
Methods: Patients who underwent TJA at our institution from 2015 to 2020 were surveyed on sports/physical activity participation before and after TJA.
Chiral Locomotion Transitions of an Active Gel and Their Chemomechanical Origin.
J Am Chem Soc
January 2025
College of Chemical Engineering, China University of Mining and Technology, Xuzhou 221116, Jiangsu, P.R. China.
Transitions between chiral rotational locomotion modes occur in a variety of active individuals and populations, such as sidewinders, self-propelled chiral droplets, and dense bacterial suspensions. Despite recent progress in the study of active matter, general principles governing rotational chiral transition remain elusive. Here, we study, experimentally and theoretically, rotational locomotion and its chiral transition in a 2D polyacrylamide (PAAm)-based BZ gel driven by Belousov-Zhabotinsky reaction-diffusion waves.
View Article and Find Full Text PDFPropulsive and braking contribution of the lower limbs, trunk, and upper limbs during underwater undulatory swimming calculated from vortices distribution: A simulation study.
J Biomech
January 2025
Faculty of Sport and Health Science, Ritsumeikan University, Japan.
Swimmers propel their bodies forward by generating vortices around themselves, which produce fluid force during underwater undulatory swimming (UUS). This study aimed to investigate the propulsive and braking contributions of the vortices of the lower limbs, trunk, and upper limbs during UUS. The kinematic data and three-dimensional digital model were collected from nine male swimmers.
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