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Preliminary Evidence for Perturbation-Based tACS-EEG Biomarkers of Gamma Activity in Alzheimer's Disease.
Int J Geriatr Psychiatry
January 2025
Precision Neuroscience & Neuromodulation Program, Gordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Background: Alzheimer's disease (AD) is characterized by impaired inhibitory circuitry and GABAergic dysfunction, which is associated with reduced fast brain oscillations in the gamma band (γ, 30-90 Hz) in several animal models. Investigating such activity in human patients could lead to the identification of novel biomarkers of diagnostic and prognostic value. The current study aimed to test a multimodal "Perturbation-based" transcranial Alternating Current Stimulation-Electroencephalography (tACS)-EEG protocol to detect how responses to tACS in AD patients correlate with patients' clinical phenotype.
View Article and Find Full Text PDFAntimicrobial agents in agricultural fertilizers produced from sewage sludge - A cause for concern?
Sci Total Environ
January 2025
University of Bath, Department of Chemistry, Bath BA2 7AY, United Kingdom; Centre of Excellence in Water-Based Early Warning Systems for Health Protection, University of Bath, Bath BA25RX, United Kingdom.
The production of organic-mineral fertilizers from sewage sludge is one of the ecological options in their management. Though, pharmaceuticals and their derivatives, which accumulate in the sludge, could be a problem due to their impacts on the environment. This manuscript aimed at better understanding of risks posed by antimicrobial agents (AAs) in sludge-based fertilizers.
View Article and Find Full Text PDFClinical and Topographic Screening for Scoliosis in Children Participating in Routine Sports: A Prevalence and Accuracy Study in a Spanish Population.
J Clin Med
January 2025
Department of Biomedical Engineering, University of Alberta, Edmonton, AB T6G 2G8, Canada.
: Idiopathic scoliosis (IS) is a common spinal deformity affecting 0.5% to 5.2% of children worldwide, with a higher reported range in Spain (0.
View Article and Find Full Text PDFAnalysis of Inflammatory Features in Suspicious Lesions for Significant Prostate Cancer on Magnetic Resonance Imaging-Are They Mimickers of Prostate Cancer?
Cancers (Basel)
December 2024
Department of Urology, Vall d'Hebron Hospital Campus, 08035 Barcelona, Spain.
Background: Inflammatory features can mimic PCa in suspicious MRI-lesions.
Objectives: To assess the incidence of inflammatory features in targeted biopsies to suspicious lesions.
Methods: A prospective analysis was conducted of 531 MRI-suspicious lesions with Prostate Imaging-Reporting and Data System (PI-RADS) scores of 3 to 5 in 364 men suspected of having PCa.
An Overview of Zika Virus and Zika Virus Induced Neuropathies.
Int J Mol Sci
December 2024
Department of Entomology, Pennsylvania State University, University Park, PA 16802, USA.
Flaviviruses pose a major public health concern across the globe. Among them, Zika virus (ZIKV) is an emerging and reemerging arthropod-borne flavivirus that has become a major international public health problem following multiple large outbreaks over the past two decades. The majority of infections caused by ZIKV exhibit mild symptoms.
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