The current article concerns human outcome-selective Pavlovian-instrumental transfer (PIT), where Pavlovian cues selectively invigorate instrumental responses that predict common rewarding outcomes. Several recent experiments have observed PIT effects that were insensitive to outcome devaluation manipulations, which has been taken as evidence of an automatic "associative" mechanism. Other similar studies observed PIT effects that were sensitive to devaluation, which suggests a more controlled, goal-directed process. Studies supporting the automatic approach have been criticized for using a biased baseline, whereas studies supporting the goal-directed approach have been criticized for priming multiple outcomes at test. The current experiment addressed both of these issues. Participants first learned to perform two instrumental responses to earn two outcomes each (R1-O1/O3, R2-O2/O4), before four Pavlovian stimuli (S1-S4) were trained to predict each outcome. One outcome that was paired with each instrumental response (O3 and O4) was then devalued, so that baseline response choice at test would be balanced. Instrumental responding was then assessed in the presence of each individual Pavlovian stimulus, so that only one outcome was primed per trial. PIT effects were observed for the valued outcomes (ts > 3.96, ps < .001) but not for the devalued outcomes (F < 1, Bayes Factor10 = .29). Hence, when baseline response choice was equated and only one outcome was primed per test trial, PIT was sensitive to outcome devaluation. The data therefore support goal-directed models of PIT. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Download full-text PDF

Source
http://dx.doi.org/10.1037/xan0000191DOI Listing

Publication Analysis

Top Keywords

pit effects
12
pavlovian-instrumental transfer
8
instrumental responses
8
observed pit
8
outcome devaluation
8
studies supporting
8
approach criticized
8
baseline response
8
response choice
8
outcome primed
8

Similar Publications

Slopes influenced by multiple faults are prone to large-scale landslides triggered by multi-regional failures. Understanding the failure process and sequence is essential for the sustainable development of mining operations. This paper presents a method combining InSAR monitoring and numerical simulation to analyze the failure processes of slopes affected by multiple faults.

View Article and Find Full Text PDF

Mechanical Strength and Mechanism Analysis of Silt Soil Cured by Straw Ash-Calcium Carbide Slag.

Materials (Basel)

January 2025

Heilongjiang Provincial Key Laboratory of Road Structure and Green Ecological Technology, Northeast Forestry University, Harbin 150090, China.

Large-scale engineering projects frequently involve pit excavation and wetland landfill operations, resulting in significant silt accumulation that occupies land and adversely affects the environment. Curing technology offers a solution for reusing this waste silt. In this study, straw ash and calcium carbide slag are proposed as effective curing agents for silt soil.

View Article and Find Full Text PDF

Enhancing the efficacy of near-infrared photoimmunotherapy through intratumoural delivery of CD44-targeting antibody-photoabsorber conjugates.

EBioMedicine

January 2025

Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan; Department of Immunopathology, World Premier International Research Center, Initiative, Immunology, Frontier Research Center, Osaka University, Osaka, Japan; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan; Center for Infectious Diseases for Education and Research, Osaka University, Osaka, Japan; Japan Agency for Medical Research and Development - Core Research for Evolutional Science and Technology, Osaka University, Osaka, Japan; Center for Advanced Modalities and DDS, Osaka University, Osaka, Japan. Electronic address:

Background: Photoimmunotherapy (PIT) is a potent modality for cancer treatment. The conventional PIT regimen involves the systemic delivery of an antibody-photoabsorber conjugate, followed by a 24-h waiting period to ensure adequate localisation on the target cells. Subsequent exposure to near-infrared (NIR) light selectively damages the target cells.

View Article and Find Full Text PDF

Purpose: To make micro-CT comparison and evaluation of sealant penetration depth in different types of fissures after heating of the material or application of vibrations.

Materials And Methods: One hundred sound third molars have been sealed as follows: group 1 (n = 20), light-cured resin sealant at room temperature, group 2 (n = 20), light-cured resin sealant, preheated to 41.0°C, group 3 (n = 20), light-cured resin sealant, preheated to 51.

View Article and Find Full Text PDF

Background/objectives: Photoimmunotherapy (PIT) is an innovative approach for the targeted therapy of cancer. In PIT, photosensitizer dyes are conjugated to tumor-specific antibodies for targeted delivery into cancer cells. Upon irradiation with visible light, the photosensitizer dye is activated and induces cancer-specific cell death.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!