Aim: To study the prevalence of additional root canal orifices of upper first permanent molars in Saudi subpopulation in Jeddah, Kingdom of Saudi Arabia, utilizing micro-computed tomography X-ray (micro-CT).

Materials And Methods: One hundred extracted upper first permanent molars of Saudi patients were included in the study. Micro-CT was used to detect the prevalence of extra root canal orifices of the permanent upper first molars.

Results: The evaluation of three-dimensional (3D) images of this study showed that of 100 upper permanent first molars scanned and analyzed, 10.53% had 6 pulp canal orifices, 35.09% had 5 pulp canal orifices, 47.37% had 4 pulp canal orifices and 7.01% had 3 pulp canal orifices.

Conclusion: The current data showed the highest prevalence of 4 and 5 root canal orifices compared to 3 and 6 root canal orifices.

Clinical Significance: The knowledge of anatomic variations of teeth before starting root canal treatment can help dentists to detect and manage all root canals successfully.

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