Objectives: Validation of acute morbidity as a novel outcome in emergency medicine.
Methods: Construct validity of acute morbidity was established by comparison to other outcomes using linear and logistic regression models.
Results: Data of 4608 patients were analysed. 1869 patients (40.6%) fulfilled the criteria for acute morbidity. Using multivariate analyses, acute morbidity was associated with outcomes such as hospitalisation (OR: 11, 95%-CI 9-13), mortality (OR 15, 95%-CI 6-49), and ICU admission (OR: 46, 95%-CI 25-96). Reliability of the construct "acute morbidity" was estimated using Cohens Kappa, which was 0.96 for intra-rater and 0.94 for inter-rater reliability.
Conclusion: Reliability of the framework for acute morbidity was high. Construct validity was shown by associations with hospitalisation, mortality, and ICU admission.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314600 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0207906 | PLOS |
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